KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGFLAM
All Species:
30.61
Human Site:
Y742
Identified Species:
61.21
UniProt:
Q63HQ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HQ2
NP_689616.2
1017
111271
Y742
F
I
G
G
V
P
N
Y
D
D
V
K
K
N
S
Chimpanzee
Pan troglodytes
XP_517796
1010
110654
Y743
F
I
G
G
V
P
N
Y
D
D
V
K
K
N
S
Rhesus Macaque
Macaca mulatta
XP_001083161
1017
111150
Y742
F
V
G
G
V
P
N
Y
D
D
V
K
K
N
S
Dog
Lupus familis
XP_853970
1017
112185
Y742
F
I
G
G
V
P
N
Y
D
D
V
K
K
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE4
1017
110717
Y742
F
I
G
G
V
P
N
Y
D
D
V
K
K
N
S
Rat
Rattus norvegicus
B4F785
1005
109652
Y738
F
I
G
G
V
P
N
Y
D
D
V
K
K
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509895
380
41684
Q119
V
T
G
Q
S
Q
G
Q
Y
S
K
I
T
F
R
Chicken
Gallus gallus
XP_425019
1062
116282
Y795
F
L
G
G
V
P
S
Y
D
T
V
K
K
N
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339765
1244
135834
Y782
Y
I
G
G
V
P
N
Y
D
I
T
K
P
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611082
1361
150280
V751
F
V
G
G
V
N
H
V
D
R
L
P
L
D
L
Honey Bee
Apis mellifera
XP_393275
929
101638
D668
A
K
A
F
Q
D
D
D
G
I
G
I
L
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787979
862
94451
R601
D
D
I
D
L
L
S
R
E
M
A
V
K
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
97.7
88
N.A.
88.4
87.5
N.A.
30.5
71.1
N.A.
48
N.A.
20.7
31.1
N.A.
30.9
Protein Similarity:
100
96.9
99
93.2
N.A.
93.2
91.6
N.A.
34.1
81.4
N.A.
62.6
N.A.
36.3
48.2
N.A.
47.9
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
6.6
80
N.A.
60
N.A.
33.3
0
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
93.3
N.A.
80
N.A.
60
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
9
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
9
0
9
9
9
75
50
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% E
% Phe:
67
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
84
75
0
0
9
0
9
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
9
0
0
0
0
0
0
17
0
17
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
9
67
67
0
0
% K
% Leu:
0
9
0
0
9
9
0
0
0
0
9
0
17
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
59
0
0
0
0
0
0
67
0
% N
% Pro:
0
0
0
0
0
67
0
0
0
0
0
9
9
0
0
% P
% Gln:
0
0
0
9
9
9
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
9
% R
% Ser:
0
0
0
0
9
0
17
0
0
9
0
0
0
9
67
% S
% Thr:
0
9
0
0
0
0
0
0
0
9
9
0
9
0
0
% T
% Val:
9
17
0
0
75
0
0
9
0
0
59
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
67
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _