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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGFLAM
All Species:
27.27
Human Site:
Y388
Identified Species:
54.55
UniProt:
Q63HQ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HQ2
NP_689616.2
1017
111271
Y388
S
E
D
I
V
I
Q
Y
P
Q
F
F
G
H
S
Chimpanzee
Pan troglodytes
XP_517796
1010
110654
Y389
S
E
D
I
V
I
Q
Y
P
Q
F
F
G
H
S
Rhesus Macaque
Macaca mulatta
XP_001083161
1017
111150
Y388
S
E
D
I
I
I
Q
Y
P
Q
F
F
G
H
S
Dog
Lupus familis
XP_853970
1017
112185
Y388
S
E
D
I
A
I
Q
Y
P
Q
F
F
G
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE4
1017
110717
Y388
S
E
D
I
F
I
Q
Y
P
Q
F
F
G
H
S
Rat
Rattus norvegicus
B4F785
1005
109652
Y384
S
E
D
I
F
I
Q
Y
P
Q
F
F
G
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509895
380
41684
Chicken
Gallus gallus
XP_425019
1062
116282
Y441
T
E
D
I
T
I
Q
Y
P
Q
F
Y
G
Y
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339765
1244
135834
S428
S
Y
Q
S
F
Q
I
S
L
E
F
K
V
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611082
1361
150280
V402
Q
E
D
I
R
A
H
V
P
R
F
A
K
R
S
Honey Bee
Apis mellifera
XP_393275
929
101638
E331
I
L
H
H
G
F
I
E
F
R
F
D
C
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787979
862
94451
Q263
V
P
T
S
K
L
Y
Q
S
F
Y
I
T
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
97.7
88
N.A.
88.4
87.5
N.A.
30.5
71.1
N.A.
48
N.A.
20.7
31.1
N.A.
30.9
Protein Similarity:
100
96.9
99
93.2
N.A.
93.2
91.6
N.A.
34.1
81.4
N.A.
62.6
N.A.
36.3
48.2
N.A.
47.9
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
0
73.3
N.A.
20
N.A.
40
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
93.3
N.A.
26.6
N.A.
46.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
67
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
67
0
0
0
0
0
9
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
25
9
0
0
9
9
84
50
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
0
59
9
0
% G
% His:
0
0
9
9
0
0
9
0
0
0
0
0
0
50
0
% H
% Ile:
9
0
0
67
9
59
17
0
0
0
0
9
0
9
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
9
9
9
0
% K
% Leu:
0
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
67
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
0
9
59
9
0
59
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
17
0
0
0
9
0
% R
% Ser:
59
0
0
17
0
0
0
9
9
0
0
0
0
0
92
% S
% Thr:
9
0
9
0
9
0
0
0
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
17
0
0
9
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
9
59
0
0
9
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _