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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGFLAM
All Species:
23.03
Human Site:
Y251
Identified Species:
46.06
UniProt:
Q63HQ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HQ2
NP_689616.2
1017
111271
Y251
S
G
R
Y
G
P
R
Y
I
T
D
M
G
A
G
Chimpanzee
Pan troglodytes
XP_517796
1010
110654
Y252
S
G
R
Y
G
P
R
Y
I
T
D
M
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001083161
1017
111150
Y251
S
G
R
Y
G
P
R
Y
I
T
D
M
G
A
G
Dog
Lupus familis
XP_853970
1017
112185
Y251
S
G
R
Y
G
P
C
Y
I
T
N
M
G
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE4
1017
110717
Y251
S
G
H
Y
G
P
G
Y
I
T
N
P
G
V
S
Rat
Rattus norvegicus
B4F785
1005
109652
Y251
S
G
R
Y
G
P
G
Y
I
T
D
T
G
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509895
380
41684
Chicken
Gallus gallus
XP_425019
1062
116282
Y298
S
G
S
Y
G
H
H
Y
I
T
E
T
V
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339765
1244
135834
I264
S
G
D
Y
D
V
Y
I
S
N
S
D
N
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611082
1361
150280
Y274
E
G
D
G
S
D
D
Y
S
Y
S
Y
K
S
D
Honey Bee
Apis mellifera
XP_393275
929
101638
A204
G
D
D
V
D
L
I
A
D
D
D
D
D
D
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787979
862
94451
P136
D
T
N
S
E
S
F
P
L
I
C
G
V
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
97.7
88
N.A.
88.4
87.5
N.A.
30.5
71.1
N.A.
48
N.A.
20.7
31.1
N.A.
30.9
Protein Similarity:
100
96.9
99
93.2
N.A.
93.2
91.6
N.A.
34.1
81.4
N.A.
62.6
N.A.
36.3
48.2
N.A.
47.9
P-Site Identity:
100
100
100
80
N.A.
60
73.3
N.A.
0
53.3
N.A.
20
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
73.3
N.A.
0
60
N.A.
20
N.A.
20
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
9
9
25
0
17
9
9
0
9
9
42
17
9
9
25
% D
% Glu:
9
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
75
0
9
59
0
17
0
0
0
0
9
50
0
42
% G
% His:
0
0
9
0
0
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
59
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% K
% Leu:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
9
17
0
9
0
0
% N
% Pro:
0
0
0
0
0
50
0
9
0
0
0
9
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
42
0
0
0
25
0
0
0
0
0
0
0
0
% R
% Ser:
67
0
9
9
9
9
0
0
17
0
17
0
0
9
17
% S
% Thr:
0
9
0
0
0
0
0
0
0
59
0
17
0
9
0
% T
% Val:
0
0
0
9
0
9
0
0
0
0
0
0
17
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
67
0
0
9
67
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _