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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EGFLAM All Species: 31.52
Human Site: S883 Identified Species: 63.03
UniProt: Q63HQ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q63HQ2 NP_689616.2 1017 111271 S883 L L L W R G D S P M R P N S D
Chimpanzee Pan troglodytes XP_517796 1010 110654 S876 L L L W R G D S P M R P N S D
Rhesus Macaque Macaca mulatta XP_001083161 1017 111150 S883 L L L W R G D S P M R P N S D
Dog Lupus familis XP_853970 1017 112185 S883 L L M W R G D S P M R P N S D
Cat Felis silvestris
Mouse Mus musculus Q4VBE4 1017 110717 S883 L L L W R G D S P M R P N S D
Rat Rattus norvegicus B4F785 1005 109652 S871 L L L W R G D S P M R P N S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509895 380 41684 N249 P W P L E P Q N Y L S F M E F
Chicken Gallus gallus XP_425019 1062 116282 S928 L L M W R G D S P M R P N S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339765 1244 135834 S915 L L L W R G E S P M R A N S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611082 1361 150280 G1226 I L W T G R Q G T T E E H D D
Honey Bee Apis mellifera XP_393275 929 101638 R798 Q A D P Q E Q R D E N D D F L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787979 862 94451 M731 L W A G H S S M T S G S D F I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 97.7 88 N.A. 88.4 87.5 N.A. 30.5 71.1 N.A. 48 N.A. 20.7 31.1 N.A. 30.9
Protein Similarity: 100 96.9 99 93.2 N.A. 93.2 91.6 N.A. 34.1 81.4 N.A. 62.6 N.A. 36.3 48.2 N.A. 47.9
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 0 93.3 N.A. 86.6 N.A. 13.3 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 N.A. 93.3 N.A. 26.6 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 59 0 9 0 0 9 17 9 75 % D
% Glu: 0 0 0 0 9 9 9 0 0 9 9 9 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 9 % F
% Gly: 0 0 0 9 9 67 0 9 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 75 75 50 9 0 0 0 0 0 9 0 0 0 0 9 % L
% Met: 0 0 17 0 0 0 0 9 0 67 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 9 0 67 0 0 % N
% Pro: 9 0 9 9 0 9 0 0 67 0 0 59 0 0 0 % P
% Gln: 9 0 0 0 9 0 25 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 67 9 0 9 0 0 67 0 0 0 0 % R
% Ser: 0 0 0 0 0 9 9 67 0 9 9 9 0 67 0 % S
% Thr: 0 0 0 9 0 0 0 0 17 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 17 9 67 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _