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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGFLAM
All Species:
24.24
Human Site:
S306
Identified Species:
48.48
UniProt:
Q63HQ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q63HQ2
NP_689616.2
1017
111271
S306
I
S
N
P
K
T
I
S
R
L
I
P
P
T
S
Chimpanzee
Pan troglodytes
XP_517796
1010
110654
S307
I
S
N
P
K
T
I
S
R
L
I
P
P
T
S
Rhesus Macaque
Macaca mulatta
XP_001083161
1017
111150
S306
I
S
N
P
K
T
I
S
R
L
V
P
P
T
S
Dog
Lupus familis
XP_853970
1017
112185
S306
K
S
N
P
K
T
V
S
R
L
V
R
P
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q4VBE4
1017
110717
S306
V
S
N
S
V
M
G
S
R
L
A
Q
P
T
S
Rat
Rattus norvegicus
B4F785
1005
109652
S302
V
S
N
S
E
M
D
S
R
L
A
Q
P
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509895
380
41684
Chicken
Gallus gallus
XP_425019
1062
116282
S353
G
S
S
S
R
L
L
S
R
V
L
T
T
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339765
1244
135834
Y317
P
G
N
G
N
V
I
Y
R
M
R
T
P
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611082
1361
150280
S324
R
K
Y
P
N
V
T
S
N
K
V
Q
M
H
I
Honey Bee
Apis mellifera
XP_393275
929
101638
C254
S
F
R
Q
R
C
Q
C
P
L
G
R
G
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787979
862
94451
G183
E
G
G
E
G
G
E
G
G
E
G
G
E
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
97.7
88
N.A.
88.4
87.5
N.A.
30.5
71.1
N.A.
48
N.A.
20.7
31.1
N.A.
30.9
Protein Similarity:
100
96.9
99
93.2
N.A.
93.2
91.6
N.A.
34.1
81.4
N.A.
62.6
N.A.
36.3
48.2
N.A.
47.9
P-Site Identity:
100
100
93.3
66.6
N.A.
53.3
53.3
N.A.
0
33.3
N.A.
33.3
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
60
66.6
N.A.
0
66.6
N.A.
40
N.A.
20
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% D
% Glu:
9
0
0
9
9
0
9
0
0
9
0
0
9
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
9
9
9
9
9
9
9
0
17
9
9
17
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
25
0
0
0
0
0
34
0
0
0
17
0
0
0
9
% I
% Lys:
9
9
0
0
34
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
9
0
0
59
9
0
0
0
9
% L
% Met:
0
0
0
0
0
17
0
0
0
9
0
0
9
0
0
% M
% Asn:
0
0
59
0
17
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
9
0
0
42
0
0
0
0
9
0
0
25
59
0
0
% P
% Gln:
0
0
0
9
0
0
9
0
0
0
0
25
0
0
0
% Q
% Arg:
9
0
9
0
17
0
0
0
67
0
9
17
0
0
0
% R
% Ser:
9
59
9
25
0
0
0
67
0
0
0
0
0
0
59
% S
% Thr:
0
0
0
0
0
34
9
0
0
0
0
17
9
59
0
% T
% Val:
17
0
0
0
9
17
9
0
0
9
25
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _