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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EGFLAM All Species: 9.7
Human Site: S127 Identified Species: 19.39
UniProt: Q63HQ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q63HQ2 NP_689616.2 1017 111271 S127 A G K G R L S S P R H V T T L
Chimpanzee Pan troglodytes XP_517796 1010 110654 G127 R G K K R M F G S D P R H S I
Rhesus Macaque Macaca mulatta XP_001083161 1017 111150 S127 A G K G R L S S P R H V T T L
Dog Lupus familis XP_853970 1017 112185 S127 T V K G R L S S P Q Y V T T L
Cat Felis silvestris
Mouse Mus musculus Q4VBE4 1017 110717 F127 T G K G R L S F P R H V T T L
Rat Rattus norvegicus B4F785 1005 109652 F127 T G K G R L S F P R H V T T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509895 380 41684
Chicken Gallus gallus XP_425019 1062 116282 M174 A G K G R P S M P R D V T T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339765 1244 135834 N125 T T D V V I G N L K V A T Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611082 1361 150280 E145 P A G N E N G E D E S G S E G
Honey Bee Apis mellifera XP_393275 929 101638 S81 Y S C A E L N S T S P S T G E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787979 862 94451 R13 T N G L K N Y R P I A N L P F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 97.7 88 N.A. 88.4 87.5 N.A. 30.5 71.1 N.A. 48 N.A. 20.7 31.1 N.A. 30.9
Protein Similarity: 100 96.9 99 93.2 N.A. 93.2 91.6 N.A. 34.1 81.4 N.A. 62.6 N.A. 36.3 48.2 N.A. 47.9
P-Site Identity: 100 20 100 73.3 N.A. 86.6 86.6 N.A. 0 80 N.A. 6.6 N.A. 0 20 N.A. 6.6
P-Site Similarity: 100 40 100 86.6 N.A. 86.6 86.6 N.A. 0 80 N.A. 26.6 N.A. 6.6 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 0 9 0 0 0 0 0 0 9 9 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 9 9 9 0 0 0 0 % D
% Glu: 0 0 0 0 17 0 0 9 0 9 0 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 9 17 0 0 0 0 0 0 9 % F
% Gly: 0 50 17 50 0 0 17 9 0 0 0 9 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 34 0 9 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 9 % I
% Lys: 0 0 59 9 9 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 9 0 50 0 0 9 0 0 0 9 0 50 % L
% Met: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 9 0 17 9 9 0 0 0 9 0 0 0 % N
% Pro: 9 0 0 0 0 9 0 0 59 0 17 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % Q
% Arg: 9 0 0 0 59 0 0 9 0 42 0 9 0 0 0 % R
% Ser: 0 9 0 0 0 0 50 34 9 9 9 9 9 9 0 % S
% Thr: 42 9 0 0 0 0 0 0 9 0 0 0 67 50 0 % T
% Val: 0 9 0 9 9 0 0 0 0 0 9 50 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 9 0 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _