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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALS2CL
All Species:
20.61
Human Site:
Y529
Identified Species:
56.67
UniProt:
Q60I27
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q60I27
NP_667340.2
953
107748
Y529
L
S
E
D
D
S
L
Y
E
G
T
F
T
R
D
Chimpanzee
Pan troglodytes
Q5BIW4
1657
183718
Y1221
L
S
E
D
D
T
I
Y
E
G
E
F
S
D
D
Rhesus Macaque
Macaca mulatta
XP_001091562
1670
184507
L1221
T
L
S
G
K
G
T
L
T
M
P
N
G
D
Y
Dog
Lupus familis
XP_541902
997
111866
Y573
L
S
E
D
D
S
L
Y
E
G
T
F
T
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60I26
952
108127
Y529
L
C
E
D
D
S
L
Y
E
G
T
F
T
R
D
Rat
Rattus norvegicus
P0C5Y8
1651
182430
Y1215
L
S
E
D
D
T
I
Y
E
G
E
F
S
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517899
881
100290
K493
E
S
D
K
E
R
P
K
A
V
L
R
S
P
G
Chicken
Gallus gallus
XP_421940
1649
182052
Y1213
L
S
E
D
D
T
V
Y
E
G
E
F
S
D
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785995
792
88418
G420
Q
K
W
E
D
I
F
G
Q
C
R
T
L
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
21.5
80
N.A.
81.3
24
N.A.
35
24.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
36.3
34.1
85.3
N.A.
89
36.3
N.A.
51.8
36.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
35.6
P-Site Identity:
100
66.6
0
100
N.A.
93.3
66.6
N.A.
6.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
86.6
0
100
N.A.
93.3
86.6
N.A.
26.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
12
67
78
0
0
0
0
0
0
0
0
45
56
% D
% Glu:
12
0
67
12
12
0
0
0
67
0
34
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
67
0
0
0
% F
% Gly:
0
0
0
12
0
12
0
12
0
67
0
0
12
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
12
12
0
0
12
0
0
0
0
0
0
0
% K
% Leu:
67
12
0
0
0
0
34
12
0
0
12
0
12
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
12
0
0
12
0
% P
% Gln:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
0
0
0
12
12
0
34
0
% R
% Ser:
0
67
12
0
0
34
0
0
0
0
0
0
45
0
0
% S
% Thr:
12
0
0
0
0
34
12
0
12
0
34
12
34
0
0
% T
% Val:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _