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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALS2CL
All Species:
18.79
Human Site:
Y345
Identified Species:
51.67
UniProt:
Q60I27
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q60I27
NP_667340.2
953
107748
Y345
P
D
C
R
C
A
E
Y
T
F
Q
A
E
G
R
Chimpanzee
Pan troglodytes
Q5BIW4
1657
183718
Y1036
P
I
S
R
S
A
K
Y
T
F
Y
K
D
P
R
Rhesus Macaque
Macaca mulatta
XP_001091562
1670
184507
Y1036
P
I
S
R
S
A
K
Y
T
F
Y
K
D
P
R
Dog
Lupus familis
XP_541902
997
111866
Y389
P
T
C
R
C
V
A
Y
T
F
R
A
E
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q60I26
952
108127
Y345
P
E
C
R
C
V
A
Y
T
F
C
R
E
G
R
Rat
Rattus norvegicus
P0C5Y8
1651
182430
Y1030
P
I
S
R
S
A
K
Y
T
F
Y
K
D
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517899
881
100290
Y319
K
E
D
H
Y
V
G
Y
W
K
E
G
K
M
C
Chicken
Gallus gallus
XP_421940
1649
182052
Y1028
P
I
S
R
S
A
K
Y
A
F
Y
K
D
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785995
792
88418
V253
H
R
H
G
N
G
L
V
I
T
L
S
G
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
21.5
80
N.A.
81.3
24
N.A.
35
24.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
36.3
34.1
85.3
N.A.
89
36.3
N.A.
51.8
36.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
35.6
P-Site Identity:
100
46.6
46.6
73.3
N.A.
66.6
46.6
N.A.
6.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
60
60
80
N.A.
73.3
60
N.A.
26.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
56
23
0
12
0
0
23
0
0
0
% A
% Cys:
0
0
34
0
34
0
0
0
0
0
12
0
0
0
12
% C
% Asp:
0
12
12
0
0
0
0
0
0
0
0
0
45
0
0
% D
% Glu:
0
23
0
0
0
0
12
0
0
0
12
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
12
12
0
0
0
0
12
12
34
0
% G
% His:
12
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
45
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
45
0
0
12
0
45
12
0
0
% K
% Leu:
0
0
0
0
0
0
12
0
0
0
12
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
78
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
12
0
78
0
0
0
0
0
0
12
12
0
0
78
% R
% Ser:
0
0
45
0
45
0
0
0
0
0
0
12
0
0
0
% S
% Thr:
0
12
0
0
0
0
0
0
67
12
0
0
0
12
0
% T
% Val:
0
0
0
0
0
34
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
89
0
0
45
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _