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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALS2CL
All Species:
7.88
Human Site:
S335
Identified Species:
21.67
UniProt:
Q60I27
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q60I27
NP_667340.2
953
107748
S335
L
G
A
G
L
E
P
S
Q
P
P
D
C
R
C
Chimpanzee
Pan troglodytes
Q5BIW4
1657
183718
Q1026
S
G
S
S
V
Q
R
Q
E
P
P
I
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001091562
1670
184507
Q1026
S
G
S
S
V
Q
R
Q
E
P
P
I
S
R
S
Dog
Lupus familis
XP_541902
997
111866
S379
L
G
A
G
L
E
P
S
E
P
P
T
C
R
C
Cat
Felis silvestris
Mouse
Mus musculus
Q60I26
952
108127
S335
L
G
S
G
R
E
T
S
V
P
P
E
C
R
C
Rat
Rattus norvegicus
P0C5Y8
1651
182430
Q1020
G
S
S
T
V
Q
R
Q
E
P
P
I
S
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517899
881
100290
A309
E
Y
K
V
P
N
K
A
L
N
K
E
D
H
Y
Chicken
Gallus gallus
XP_421940
1649
182052
Q1018
A
G
G
N
V
P
R
Q
E
P
P
I
S
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785995
792
88418
Q243
E
K
Y
M
G
L
W
Q
D
D
H
R
H
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
21.5
80
N.A.
81.3
24
N.A.
35
24.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
36.3
34.1
85.3
N.A.
89
36.3
N.A.
51.8
36.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
35.6
P-Site Identity:
100
26.6
26.6
86.6
N.A.
66.6
20
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
53.3
53.3
93.3
N.A.
80
46.6
N.A.
13.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
34
% C
% Asp:
0
0
0
0
0
0
0
0
12
12
0
12
12
0
0
% D
% Glu:
23
0
0
0
0
34
0
0
56
0
0
23
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
67
12
34
12
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
12
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
45
0
0
0
% I
% Lys:
0
12
12
0
0
0
12
0
0
0
12
0
0
0
0
% K
% Leu:
34
0
0
0
23
12
0
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
12
0
0
0
12
0
0
0
0
12
% N
% Pro:
0
0
0
0
12
12
23
0
0
78
78
0
0
0
0
% P
% Gln:
0
0
0
0
0
34
0
56
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
45
0
0
0
0
12
0
78
0
% R
% Ser:
23
12
45
23
0
0
0
34
0
0
0
0
45
0
45
% S
% Thr:
0
0
0
12
0
0
12
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
12
45
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _