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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
17.58
Human Site:
Y403
Identified Species:
42.96
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
Y403
R
N
V
F
C
G
T
Y
N
V
R
I
L
S
D
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
L63
S
N
R
K
I
H
L
L
D
I
I
Q
V
K
A
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
Y403
R
N
I
F
C
G
T
Y
N
V
R
I
L
S
D
Dog
Lupus familis
XP_536650
1059
121515
Y407
R
N
I
F
C
G
T
Y
N
I
R
I
L
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
M408
Q
E
T
Q
L
V
Q
M
E
E
R
N
V
F
C
Rat
Rattus norvegicus
XP_001077639
1016
115893
E400
T
Q
L
I
Q
M
E
E
R
N
V
F
C
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
Y488
R
N
V
F
C
G
T
Y
N
V
R
I
L
T
D
Chicken
Gallus gallus
XP_415592
693
76558
V82
V
L
T
D
R
S
S
V
G
I
Y
G
W
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
L241
G
V
Y
N
T
S
V
L
L
E
R
E
D
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
Y450
R
N
I
Y
C
G
A
Y
N
V
M
V
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
6.6
93.3
86.6
N.A.
6.6
0
N.A.
93.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
26.6
100
100
N.A.
20
6.6
N.A.
100
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
50
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
10
0
50
% D
% Glu:
0
10
0
0
0
0
10
10
10
20
0
10
0
0
0
% E
% Phe:
0
0
0
40
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
10
0
0
0
0
50
0
0
10
0
0
10
0
20
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
30
10
10
0
0
0
0
30
10
40
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
20
0
% K
% Leu:
0
10
10
0
10
0
10
20
10
0
0
0
50
0
0
% L
% Met:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
0
% M
% Asn:
0
60
0
10
0
0
0
0
50
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
10
10
0
10
0
0
0
0
10
0
0
0
% Q
% Arg:
50
0
10
0
10
0
0
0
10
0
60
0
0
0
10
% R
% Ser:
10
0
0
0
0
20
10
0
0
0
0
0
0
40
10
% S
% Thr:
10
0
20
0
10
0
40
0
0
0
0
0
0
10
10
% T
% Val:
10
10
20
0
0
10
10
10
0
40
10
10
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
10
10
0
0
0
50
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _