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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
5.15
Human Site:
Y252
Identified Species:
12.59
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
Y252
G
D
I
T
K
P
G
Y
D
P
C
N
L
L
V
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
Y252
G
G
I
T
K
P
G
Y
D
P
C
N
L
L
V
Dog
Lupus familis
XP_536650
1059
121515
S252
F
S
R
K
V
G
M
S
K
A
E
S
T
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
L255
G
K
G
G
M
S
R
L
G
D
D
P
C
N
L
Rat
Rattus norvegicus
XP_001077639
1016
115893
G250
N
K
E
I
F
G
R
G
G
T
S
R
L
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
F270
S
H
H
W
Q
M
G
F
G
V
E
K
A
M
P
Chicken
Gallus gallus
XP_415592
693
76558
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
Y91
T
S
G
K
D
Y
T
Y
A
R
S
R
A
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
L300
C
S
A
S
L
V
S
L
D
P
T
C
V
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
0
93.3
0
N.A.
6.6
6.6
N.A.
6.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
93.3
6.6
N.A.
13.3
6.6
N.A.
26.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
10
0
0
20
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
20
10
10
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
30
10
10
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
20
0
0
0
0
% E
% Phe:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
30
10
20
10
0
20
30
10
30
0
0
0
0
10
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
20
0
20
20
0
0
0
10
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
20
0
0
0
0
30
30
20
% L
% Met:
0
0
0
0
10
10
10
0
0
0
0
0
0
10
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
20
0
10
0
% N
% Pro:
0
0
0
0
0
20
0
0
0
30
0
10
0
10
20
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
20
0
0
10
0
20
0
0
0
% R
% Ser:
10
30
0
10
0
10
10
10
0
0
20
10
0
0
10
% S
% Thr:
10
0
0
20
0
0
10
0
0
10
10
0
10
0
0
% T
% Val:
0
0
0
0
10
10
0
0
0
10
0
0
10
10
20
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _