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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
5.76
Human Site:
T974
Identified Species:
14.07
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
T974
K
E
R
P
R
I
Y
T
A
L
D
P
F
R
V
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
R604
Y
T
A
L
D
P
F
R
V
N
T
E
F
V
L
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
L974
R
P
R
I
Y
T
A
L
D
P
L
R
V
N
T
Dog
Lupus familis
XP_536650
1059
121515
K981
K
E
R
P
R
F
Y
K
T
L
D
P
F
R
M
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
T952
K
E
R
P
R
F
Y
T
T
L
D
P
L
R
M
Rat
Rattus norvegicus
XP_001077639
1016
115893
L940
R
P
R
F
Y
T
T
L
N
P
L
R
M
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
P1039
E
R
P
R
F
T
V
P
D
P
Y
R
V
D
G
Chicken
Gallus gallus
XP_415592
693
76558
S621
A
H
G
A
R
N
P
S
Q
A
D
S
G
F
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
K780
V
T
C
L
E
D
D
K
T
P
Q
G
L
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
S1218
S
E
T
K
R
S
E
S
H
Q
K
P
S
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
6.6
6.6
73.3
N.A.
73.3
6.6
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
20
13.3
80
N.A.
80
13.3
N.A.
6.6
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
10
0
10
10
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
10
0
20
0
40
0
0
10
0
% D
% Glu:
10
40
0
0
10
0
10
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
10
20
10
0
0
0
0
0
30
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
10
% G
% His:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
30
0
0
10
0
0
0
20
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
20
0
0
0
20
0
30
20
0
20
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
20
% M
% Asn:
0
0
0
0
0
10
0
0
10
10
0
0
0
20
0
% N
% Pro:
0
20
10
30
0
10
10
10
0
40
0
40
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% Q
% Arg:
20
10
50
10
50
0
0
10
0
0
0
30
0
30
10
% R
% Ser:
10
0
0
0
0
10
0
20
0
0
0
10
10
0
0
% S
% Thr:
0
20
10
0
0
30
10
20
30
0
10
0
0
10
30
% T
% Val:
10
0
0
0
0
0
10
0
10
0
0
0
20
10
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
20
0
30
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _