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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
5.45
Human Site:
S916
Identified Species:
13.33
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
S916
P
Q
P
M
I
I
R
S
R
F
S
G
S
L
K
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
K547
S
R
F
S
G
S
L
K
G
G
D
Q
V
T
S
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
S916
P
Q
P
M
I
I
R
S
R
F
S
G
S
L
K
Dog
Lupus familis
XP_536650
1059
121515
P923
P
Q
P
V
I
I
R
P
R
F
E
S
S
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
P894
P
Q
P
S
L
I
R
P
K
V
S
D
S
L
R
Rat
Rattus norvegicus
XP_001077639
1016
115893
P883
P
Q
P
S
L
I
R
P
K
V
S
D
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
P982
C
G
S
L
K
N
V
P
R
R
A
E
P
S
P
Chicken
Gallus gallus
XP_415592
693
76558
T564
R
S
Y
S
D
S
L
T
M
K
R
I
S
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
F723
D
T
C
R
Q
P
S
F
Q
T
S
T
K
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
P1125
P
K
A
N
L
I
R
P
Q
T
A
Q
V
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
0
100
66.6
N.A.
53.3
53.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
6.6
100
80
N.A.
73.3
73.3
N.A.
20
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
20
0
0
0
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
10
0
0
0
0
0
10
20
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
10
0
30
0
0
0
0
0
% F
% Gly:
0
10
0
0
10
0
0
0
10
10
0
20
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
30
60
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
10
20
10
0
0
10
10
20
% K
% Leu:
0
0
0
10
30
0
20
0
0
0
0
0
0
60
0
% L
% Met:
0
0
0
20
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
0
50
0
0
10
0
50
0
0
0
0
10
0
30
% P
% Gln:
0
50
0
0
10
0
0
0
20
0
0
20
0
0
0
% Q
% Arg:
10
10
0
10
0
0
60
0
40
10
10
0
0
0
30
% R
% Ser:
10
10
10
40
0
20
10
20
0
0
50
10
60
10
10
% S
% Thr:
0
10
0
0
0
0
0
10
0
20
0
10
0
10
0
% T
% Val:
0
0
0
10
0
0
10
0
0
20
0
0
20
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _