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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
13.94
Human Site:
S589
Identified Species:
34.07
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
S589
F
D
Q
W
H
L
L
S
G
S
T
D
G
L
V
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
M234
G
K
Y
E
R
C
L
M
A
F
K
H
P
K
E
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
S589
F
D
Q
W
H
L
L
S
G
S
T
D
G
L
V
Dog
Lupus familis
XP_536650
1059
121515
S593
F
D
Q
W
H
L
L
S
G
S
A
D
G
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
T578
V
K
V
W
H
V
V
T
A
Q
L
Q
K
T
L
Rat
Rattus norvegicus
XP_001077639
1016
115893
A569
K
V
W
H
V
V
T
A
Q
L
Q
K
T
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
G668
G
S
V
X
X
X
X
G
N
P
I
N
S
I
N
Chicken
Gallus gallus
XP_415592
693
76558
V251
S
G
C
D
R
G
L
V
K
V
W
H
A
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
Q410
I
R
Q
I
S
G
H
Q
G
A
V
L
C
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
S652
V
D
D
W
H
I
I
S
G
S
M
D
G
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
6.6
100
93.3
N.A.
13.3
6.6
N.A.
0
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
6.6
100
93.3
N.A.
40
20
N.A.
13.3
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
20
10
10
0
10
0
0
% A
% Cys:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
40
10
10
0
0
0
0
0
0
0
40
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
30
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
20
10
0
0
0
20
0
10
50
0
0
0
40
10
0
% G
% His:
0
0
0
10
50
0
10
0
0
0
0
20
0
0
0
% H
% Ile:
10
0
0
10
0
10
10
0
0
0
10
0
0
10
0
% I
% Lys:
10
20
0
0
0
0
0
0
10
0
10
10
10
10
0
% K
% Leu:
0
0
0
0
0
30
50
0
0
10
10
10
0
50
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% P
% Gln:
0
0
40
0
0
0
0
10
10
10
10
10
0
0
0
% Q
% Arg:
0
10
0
0
20
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
10
0
0
40
0
40
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
20
0
10
10
20
% T
% Val:
20
10
20
0
10
20
10
10
0
10
10
0
0
0
40
% V
% Trp:
0
0
10
50
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _