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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW10
All Species:
10
Human Site:
S186
Identified Species:
24.44
UniProt:
Q5XX13
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5XX13
NP_113644.3
1052
119760
S186
F
S
P
E
K
D
H
S
S
K
S
A
T
S
Q
Chimpanzee
Pan troglodytes
XP_001146277
676
76116
Rhesus Macaque
Macaca mulatta
XP_001084872
1050
119876
S186
F
S
P
E
K
D
D
S
S
K
S
V
T
S
Q
Dog
Lupus familis
XP_536650
1059
121515
N186
F
F
P
E
K
D
Y
N
P
Q
T
E
T
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUS0
1030
117673
S189
F
F
P
E
K
K
Y
S
G
T
Q
D
T
S
Y
Rat
Rattus norvegicus
XP_001077639
1016
115893
P184
A
S
N
V
I
F
F
P
E
K
T
Y
N
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510270
1115
125614
S204
P
E
R
R
K
N
L
S
S
S
S
S
S
S
V
Chicken
Gallus gallus
XP_415592
693
76558
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692449
852
95928
G25
W
S
C
R
G
E
D
G
D
F
N
I
C
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794564
1304
145734
T234
E
N
E
S
L
A
D
T
V
F
S
Y
K
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.7
94.1
77.4
N.A.
69.3
68.3
N.A.
41.9
29
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
61
96.5
87.1
N.A.
80.9
80.5
N.A.
59.3
43.1
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
0
86.6
46.6
N.A.
46.6
13.3
N.A.
33.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
86.6
73.3
N.A.
53.3
26.6
N.A.
53.3
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
30
30
0
10
0
0
10
0
0
0
% D
% Glu:
10
10
10
40
0
10
0
0
10
0
0
10
0
0
0
% E
% Phe:
40
20
0
0
0
10
10
0
0
20
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
10
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
50
10
0
0
0
30
0
0
10
0
0
% K
% Leu:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
10
0
10
0
0
10
0
10
0
0
% N
% Pro:
10
0
40
0
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
20
% Q
% Arg:
0
0
10
20
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
40
0
10
0
0
0
40
30
10
40
10
10
60
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
20
0
40
0
10
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
10
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
20
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _