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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF219
All Species:
22.73
Human Site:
S115
Identified Species:
55.56
UniProt:
Q5W0B1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5W0B1
NP_078822.3
726
81116
S115
K
E
V
E
E
L
K
S
K
N
L
S
L
E
S
Chimpanzee
Pan troglodytes
XP_001142348
726
81097
S115
K
E
V
E
E
L
K
S
K
N
L
S
L
E
S
Rhesus Macaque
Macaca mulatta
XP_001090200
726
81171
S115
K
E
V
E
E
L
K
S
K
N
L
S
L
E
S
Dog
Lupus familis
XP_534154
717
80206
S115
K
E
V
E
D
L
K
S
K
N
L
S
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Y0
722
79940
S115
K
E
V
E
E
L
K
S
K
N
L
S
L
E
S
Rat
Rattus norvegicus
NP_001101859
724
80012
S115
K
E
V
E
E
L
K
S
K
N
L
S
L
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505452
732
80873
G113
K
E
V
E
E
L
R
G
Q
N
L
S
L
E
S
Chicken
Gallus gallus
XP_416999
781
86351
D186
K
E
V
E
E
L
K
D
R
N
L
N
L
Q
T
Frog
Xenopus laevis
NP_001085271
659
74465
G73
K
D
I
I
G
G
T
G
E
N
E
C
A
L
D
Zebra Danio
Brachydanio rerio
XP_001343289
544
59472
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.6
91.7
N.A.
80.7
79.6
N.A.
65
55.3
40.5
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.9
94.9
N.A.
89.2
87.8
N.A.
77.5
68.6
55.9
51.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
80
66.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
80
0
80
70
0
0
0
10
0
10
0
0
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
90
0
0
0
0
0
70
0
60
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
80
0
0
0
0
80
0
80
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
90
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
60
0
0
0
70
0
0
70
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _