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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPK All Species: 21.52
Human Site: Y206 Identified Species: 39.44
UniProt: Q5VXJ0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VXJ0 NP_001073987.1 399 45563 Y206 A P V V T V K Y T Q S P M K K
Chimpanzee Pan troglodytes XP_001138639 514 58447 Y321 A P V V T V K Y T Q S P M K K
Rhesus Macaque Macaca mulatta XP_001082335 408 46487 Y215 A P V V T L K Y T R S P M K K
Dog Lupus familis XP_543591 374 43179 S193 L K K F T T L S R E V V K A L
Cat Felis silvestris
Mouse Mus musculus Q8BM14 398 45224 Y205 A P V A T V K Y T R S P M K K
Rat Rattus norvegicus P04634 395 44570 Y205 A P V A T V K Y T Q S P L K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506638 397 45066 Y204 A P V A T V K Y A K S P G T K
Chicken Gallus gallus XP_421661 373 42666 F193 P L T K L G A F P D L L I K N
Frog Xenopus laevis NP_001089697 404 45661 F214 A P V A T V K F S K S P L A K
Zebra Danio Brachydanio rerio NP_998569 396 44722 M206 A P V A T V G M T K S P M T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46108 394 44883 N198 G P A A Y M G N M K S P L T R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67ZU1 418 46029 H223 S P V A Y L S H M T T V I G D
Baker's Yeast Sacchar. cerevisiae P34163 548 62961 P233 A I A P A M T P K G L H N R I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.4 93.6 77.6 N.A. 80.9 62.9 N.A. 55.8 55.1 56.4 57.6 N.A. 33.3 N.A. N.A. N.A.
Protein Similarity: 100 77.4 96.3 85.9 N.A. 91.2 79.1 N.A. 71.4 72.1 73.2 71.4 N.A. 55.3 N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 6.6 N.A. 86.6 86.6 N.A. 66.6 6.6 60 66.6 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 93.3 93.3 N.A. 73.3 20 86.6 73.3 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32 21.9 N.A.
Protein Similarity: N.A. N.A. N.A. 52.6 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 70 0 16 54 8 0 8 0 8 0 0 0 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 16 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 8 16 0 0 8 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 16 0 8 % I
% Lys: 0 8 8 8 0 0 54 0 8 31 0 0 8 47 62 % K
% Leu: 8 8 0 0 8 16 8 0 0 0 16 8 24 0 8 % L
% Met: 0 0 0 0 0 16 0 8 16 0 0 0 39 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % N
% Pro: 8 77 0 8 0 0 0 8 8 0 0 70 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 24 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 16 0 0 0 8 8 % R
% Ser: 8 0 0 0 0 0 8 8 8 0 70 0 0 0 0 % S
% Thr: 0 0 8 0 70 8 8 0 47 8 8 0 0 24 0 % T
% Val: 0 0 70 24 0 54 0 0 0 0 8 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 16 0 0 47 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _