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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPK All Species: 17.27
Human Site: S280 Identified Species: 31.67
UniProt: Q5VXJ0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5VXJ0 NP_001073987.1 399 45563 S280 S R L D V Y L S H N P A G T S
Chimpanzee Pan troglodytes XP_001138639 514 58447 S395 S R L D V Y L S H N P A G T S
Rhesus Macaque Macaca mulatta XP_001082335 408 46487 S289 S R L D V Y L S H N P A G T S
Dog Lupus familis XP_543591 374 43179 N265 S A G T S V Q N M L H W A Q A
Cat Felis silvestris
Mouse Mus musculus Q8BM14 398 45224 S279 S R L D V Y L S Q S P A G T S
Rat Rattus norvegicus P04634 395 44570 G279 S R F D V Y L G H N P A G T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506638 397 45066 A278 S R A N V Y V A H A P A G T S
Chicken Gallus gallus XP_421661 373 42666 N266 P A G T S V Q N M I H W S Q A
Frog Xenopus laevis NP_001089697 404 45661 S288 S R V D V Y S S H C P S G T S
Zebra Danio Brachydanio rerio NP_998569 396 44722 A280 S R T P V Y T A H C P A G T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46108 394 44883 A276 E L L E H I K A T S P A G A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67ZU1 418 46029 A295 S T I D L F L A N E P Q S T S
Baker's Yeast Sacchar. cerevisiae P34163 548 62961 A306 R Q K I A S Y A K L Y S T T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.4 93.6 77.6 N.A. 80.9 62.9 N.A. 55.8 55.1 56.4 57.6 N.A. 33.3 N.A. N.A. N.A.
Protein Similarity: 100 77.4 96.3 85.9 N.A. 91.2 79.1 N.A. 71.4 72.1 73.2 71.4 N.A. 55.3 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 86.6 86.6 N.A. 66.6 0 73.3 66.6 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 93.3 86.6 N.A. 86.6 13.3 86.6 73.3 N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32 21.9 N.A.
Protein Similarity: N.A. N.A. N.A. 52.6 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 40 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 8 0 0 39 0 8 0 62 8 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % C
% Asp: 0 0 0 54 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 16 0 0 0 0 8 0 0 0 0 70 0 0 % G
% His: 0 0 0 0 8 0 0 0 54 0 16 0 0 0 0 % H
% Ile: 0 0 8 8 0 8 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 8 0 8 0 0 0 0 0 0 % K
% Leu: 0 8 39 0 8 0 47 0 0 16 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 16 8 31 0 0 0 0 0 % N
% Pro: 8 0 0 8 0 0 0 0 0 0 77 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 16 0 8 0 0 8 0 16 0 % Q
% Arg: 8 62 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 77 0 0 0 16 8 8 39 0 16 0 16 16 0 85 % S
% Thr: 0 8 8 16 0 0 8 0 8 0 0 0 8 77 0 % T
% Val: 0 0 8 0 62 16 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % W
% Tyr: 0 0 0 0 0 62 8 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _