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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM69B
All Species:
9.09
Human Site:
T391
Identified Species:
22.22
UniProt:
Q5VUD6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VUD6
NP_689634.2
431
48583
T391
D
L
R
E
E
L
G
T
Q
L
R
T
C
T
T
Chimpanzee
Pan troglodytes
XP_520376
551
60658
T511
D
L
R
E
E
L
G
T
Q
L
R
T
C
T
T
Rhesus Macaque
Macaca mulatta
XP_001094140
422
47003
T382
D
L
R
E
E
L
G
T
Q
L
R
T
C
T
T
Dog
Lupus familis
XP_548369
430
48435
K390
D
L
R
Q
E
L
G
K
Q
L
R
T
C
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99ML4
431
48773
K391
G
L
Y
E
E
L
G
K
Q
L
R
T
C
T
T
Rat
Rattus norvegicus
Q5FVL3
431
48819
K391
D
L
Y
E
E
L
G
K
Q
L
R
T
C
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512336
417
47364
K377
D
L
R
E
E
L
Q
K
Q
L
R
T
C
T
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCL6
410
46973
K370
E
I
R
D
E
L
E
K
Q
I
Y
S
C
I
A
Zebra Danio
Brachydanio rerio
Q1RLQ5
428
48574
K388
H
L
Q
E
E
L
E
K
Q
L
Y
A
C
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192983
336
38418
V297
E
I
E
E
K
L
K
V
T
F
D
R
C
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.3
81.9
88.6
N.A.
88.8
88.4
N.A.
67.5
N.A.
47
45.4
N.A.
N.A.
N.A.
N.A.
29.7
Protein Similarity:
100
77.6
86.3
93
N.A.
92.3
92.1
N.A.
80
N.A.
65.1
63.8
N.A.
N.A.
N.A.
N.A.
47.1
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
86.6
N.A.
33.3
46.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
86.6
N.A.
66.6
53.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% C
% Asp:
60
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
20
0
10
80
90
0
20
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
60
0
0
0
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
0
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
10
60
0
0
0
0
0
10
0
% K
% Leu:
0
80
0
0
0
100
0
0
0
80
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
10
0
90
0
0
0
0
0
0
% Q
% Arg:
0
0
60
0
0
0
0
0
0
0
70
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
30
10
0
0
70
0
70
70
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _