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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12L1
All Species:
8.48
Human Site:
S235
Identified Species:
20.74
UniProt:
Q5VU92
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VU92
NP_848565.2
463
51201
S235
D
D
T
V
A
W
H
S
E
V
G
L
P
V
Y
Chimpanzee
Pan troglodytes
XP_529143
510
55813
S282
N
G
S
I
A
W
H
S
E
V
G
L
P
V
Y
Rhesus Macaque
Macaca mulatta
XP_001089560
463
50773
S235
N
G
S
I
A
W
H
S
E
V
G
L
P
V
Y
Dog
Lupus familis
XP_549235
578
63266
N350
N
G
S
I
A
W
H
N
D
A
G
L
P
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW4
469
51604
N241
N
G
S
I
P
W
H
N
N
S
G
I
P
R
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
A205
L
S
Q
V
P
V
Y
A
H
I
T
H
R
A
L
Frog
Xenopus laevis
Q63ZP7
446
49593
G220
N
K
S
D
F
Q
H
G
L
S
R
V
P
V
Y
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
N254
S
Q
A
E
K
R
Q
N
V
E
G
V
P
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
A248
I
D
N
D
L
A
E
A
P
D
K
A
D
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
E224
D
R
V
Q
D
I
N
E
T
T
L
V
P
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
87.2
63.4
N.A.
74.1
N.A.
N.A.
N.A.
57.2
54.4
53.5
N.A.
N.A.
38
N.A.
39.3
Protein Similarity:
100
69
92.8
70.9
N.A.
83.5
N.A.
N.A.
N.A.
70.1
70.6
66.5
N.A.
N.A.
57.2
N.A.
57.8
P-Site Identity:
100
73.3
73.3
53.3
N.A.
33.3
N.A.
N.A.
N.A.
6.6
26.6
20
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
66.6
N.A.
N.A.
N.A.
26.6
46.6
33.3
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
40
10
0
20
0
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
20
0
20
10
0
0
0
10
10
0
0
10
0
0
% D
% Glu:
0
0
0
10
0
0
10
10
30
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
40
0
0
0
0
0
10
0
0
60
0
0
10
0
% G
% His:
0
0
0
0
0
0
60
0
10
0
0
10
0
0
0
% H
% Ile:
10
0
0
40
0
10
0
0
0
10
0
10
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
10
0
0
0
10
0
0
0
10
0
10
40
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
10
0
0
0
10
30
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
0
0
0
10
0
0
0
80
0
10
% P
% Gln:
0
10
10
10
0
10
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
10
0
0
0
0
10
0
10
10
0
% R
% Ser:
10
10
50
0
0
0
0
30
0
20
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
10
10
0
0
0
0
% T
% Val:
0
0
10
20
0
10
0
0
10
30
0
30
0
60
0
% V
% Trp:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
80
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _