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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12L1
All Species:
1.21
Human Site:
S139
Identified Species:
2.96
UniProt:
Q5VU92
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VU92
NP_848565.2
463
51201
S139
R
I
P
L
L
R
D
S
E
A
R
L
A
Q
D
Chimpanzee
Pan troglodytes
XP_529143
510
55813
A182
D
P
E
L
S
A
D
A
E
A
Q
P
S
P
P
Rhesus Macaque
Macaca mulatta
XP_001089560
463
50773
K139
R
I
P
L
M
R
D
K
E
A
G
L
A
Q
A
Dog
Lupus familis
XP_549235
578
63266
R254
R
I
P
L
M
R
D
R
G
P
W
L
A
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW4
469
51604
R145
R
I
P
L
M
R
D
R
G
P
G
Q
T
R
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
S123
H
A
I
E
L
N
P
S
R
T
L
L
A
T
G
Frog
Xenopus laevis
Q63ZP7
446
49593
R126
R
I
P
I
L
K
D
R
E
P
I
N
G
S
H
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
R136
R
I
P
M
L
K
D
R
E
G
R
G
E
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
R156
Q
I
P
S
L
H
G
R
Q
I
N
S
G
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
P132
R
S
L
P
S
R
K
P
E
T
F
P
V
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
87.2
63.4
N.A.
74.1
N.A.
N.A.
N.A.
57.2
54.4
53.5
N.A.
N.A.
38
N.A.
39.3
Protein Similarity:
100
69
92.8
70.9
N.A.
83.5
N.A.
N.A.
N.A.
70.1
70.6
66.5
N.A.
N.A.
57.2
N.A.
57.8
P-Site Identity:
100
26.6
73.3
60
N.A.
40
N.A.
N.A.
N.A.
26.6
40
46.6
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
100
46.6
80
66.6
N.A.
53.3
N.A.
N.A.
N.A.
26.6
53.3
60
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
10
0
30
0
0
40
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
70
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
10
0
0
0
0
60
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
20
10
20
10
20
10
20
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
70
10
10
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
20
10
10
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
50
50
0
0
0
0
0
10
40
0
0
0
% L
% Met:
0
0
0
10
30
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
10
10
0
10
10
% N
% Pro:
0
10
70
10
0
0
10
10
0
30
0
20
0
10
10
% P
% Gln:
10
0
0
0
0
0
0
0
10
0
10
10
0
30
0
% Q
% Arg:
70
0
0
0
0
50
0
50
10
0
20
0
0
10
0
% R
% Ser:
0
10
0
10
20
0
0
20
0
0
0
10
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
20
0
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _