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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEX3C
All Species:
7.27
Human Site:
S586
Identified Species:
16
UniProt:
Q5U5Q3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5Q3
NP_057710.3
659
69366
S586
A
F
S
N
G
T
N
S
Y
S
S
S
N
G
G
Chimpanzee
Pan troglodytes
XP_523137
572
58958
S511
S
S
S
S
S
S
S
S
G
L
R
R
K
G
S
Rhesus Macaque
Macaca mulatta
XP_001096989
464
49865
C416
R
K
H
D
C
V
I
C
F
E
N
E
V
I
A
Dog
Lupus familis
XP_533399
485
52261
C437
R
K
H
D
C
V
I
C
F
E
N
E
V
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q05A36
652
68555
S579
A
F
S
N
G
T
N
S
Y
S
S
S
N
G
G
Rat
Rattus norvegicus
NP_001100847
464
49836
C416
R
K
H
D
C
V
I
C
F
E
N
E
V
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509290
537
58400
D485
P
E
S
R
R
K
H
D
C
V
I
C
F
E
N
Chicken
Gallus gallus
XP_418202
443
47323
C395
S
S
R
E
C
M
V
C
F
E
S
E
V
I
A
Frog
Xenopus laevis
A1L3F4
507
54145
C459
G
S
R
E
C
S
I
C
F
E
S
E
V
I
A
Zebra Danio
Brachydanio rerio
NP_001074462
537
57239
V488
K
G
S
R
D
C
S
V
C
F
E
S
E
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175528
491
52555
S443
K
K
Q
C
M
V
C
S
D
N
E
I
V
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23
70.4
67.3
N.A.
93
70.1
N.A.
68.1
40.6
48.7
27
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
36.1
70.4
70.1
N.A.
93.9
70.2
N.A.
72.5
48.2
56.7
41.2
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
20
0
0
N.A.
100
0
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
46.6
20
20
N.A.
100
20
N.A.
13.3
20
20
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
0
0
0
0
10
55
% A
% Cys:
0
0
0
10
46
10
10
46
19
0
0
10
0
0
0
% C
% Asp:
0
0
0
28
10
0
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
10
0
19
0
0
0
0
0
46
19
46
10
10
0
% E
% Phe:
0
19
0
0
0
0
0
0
46
10
0
0
10
0
0
% F
% Gly:
10
10
0
0
19
0
0
0
10
0
0
0
0
28
19
% G
% His:
0
0
28
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
37
0
0
0
10
10
0
46
10
% I
% Lys:
19
37
0
0
0
10
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
0
19
0
0
10
28
0
19
0
10
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
28
0
19
19
10
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
19
28
46
10
10
19
19
37
0
19
37
28
0
0
10
% S
% Thr:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
37
10
10
0
10
0
0
55
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _