KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEX3C
All Species:
8.48
Human Site:
S415
Identified Species:
18.67
UniProt:
Q5U5Q3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5Q3
NP_057710.3
659
69366
S415
H
Y
N
G
T
D
V
S
F
E
G
G
T
L
G
Chimpanzee
Pan troglodytes
XP_523137
572
58958
G340
N
G
N
N
N
N
N
G
N
G
Y
T
Y
T
A
Rhesus Macaque
Macaca mulatta
XP_001096989
464
49865
S245
P
S
R
A
R
M
I
S
N
Y
R
N
D
S
S
Dog
Lupus familis
XP_533399
485
52261
S266
P
S
R
A
R
M
I
S
N
Y
R
N
D
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q05A36
652
68555
S408
H
Y
N
G
T
D
V
S
F
E
G
G
T
L
G
Rat
Rattus norvegicus
NP_001100847
464
49836
S245
P
S
R
A
R
M
M
S
N
Y
R
N
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509290
537
58400
T314
N
P
V
P
P
S
R
T
R
M
I
S
N
Y
R
Chicken
Gallus gallus
XP_418202
443
47323
S224
D
S
L
S
S
L
G
S
A
S
T
E
S
F
Y
Frog
Xenopus laevis
A1L3F4
507
54145
T288
T
D
S
Y
F
G
G
T
R
M
A
D
Y
S
P
Zebra Danio
Brachydanio rerio
NP_001074462
537
57239
N317
Y
T
A
S
S
N
G
N
N
N
N
N
N
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175528
491
52555
N272
I
Q
R
S
S
S
D
N
Y
F
F
P
T
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23
70.4
67.3
N.A.
93
70.1
N.A.
68.1
40.6
48.7
27
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
36.1
70.4
70.1
N.A.
93.9
70.2
N.A.
72.5
48.2
56.7
41.2
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
6.6
6.6
6.6
N.A.
100
6.6
N.A.
0
6.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
13.3
13.3
N.A.
100
13.3
N.A.
13.3
20
13.3
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
28
0
0
0
0
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
19
10
0
0
0
0
10
28
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
19
0
10
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
19
10
10
0
0
10
0
% F
% Gly:
0
10
0
19
0
10
28
10
0
10
19
19
0
0
19
% G
% His:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
19
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
10
0
0
0
0
0
0
0
19
0
% L
% Met:
0
0
0
0
0
28
10
0
0
19
0
0
0
0
0
% M
% Asn:
19
0
28
10
10
19
10
19
46
10
10
37
19
0
19
% N
% Pro:
28
10
0
10
10
0
0
0
0
0
0
10
0
0
10
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
37
0
28
0
10
0
19
0
28
0
0
0
10
% R
% Ser:
0
37
10
28
28
19
0
55
0
10
0
10
10
37
28
% S
% Thr:
10
10
0
0
19
0
0
19
0
0
10
10
28
19
0
% T
% Val:
0
0
10
0
0
0
19
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
0
10
0
0
0
0
10
28
10
0
19
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _