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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEX3C
All Species:
11.52
Human Site:
S364
Identified Species:
25.33
UniProt:
Q5U5Q3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5U5Q3
NP_057710.3
659
69366
S364
H
T
Y
I
V
T
P
S
R
D
K
E
P
V
F
Chimpanzee
Pan troglodytes
XP_523137
572
58958
L295
R
N
D
S
S
S
S
L
G
S
A
S
T
D
S
Rhesus Macaque
Macaca mulatta
XP_001096989
464
49865
T200
E
M
H
I
A
M
R
T
G
N
Y
I
E
L
N
Dog
Lupus familis
XP_533399
485
52261
T221
E
M
H
I
A
M
R
T
G
N
Y
I
E
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q05A36
652
68555
S357
H
T
Y
I
V
T
P
S
R
D
K
E
P
V
F
Rat
Rattus norvegicus
NP_001100847
464
49836
T200
E
M
H
I
A
M
R
T
G
N
Y
I
E
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509290
537
58400
I269
R
E
E
I
E
M
H
I
A
M
R
T
G
N
Y
Chicken
Gallus gallus
XP_418202
443
47323
N179
F
V
D
V
N
A
D
N
D
F
H
T
N
G
T
Frog
Xenopus laevis
A1L3F4
507
54145
V243
F
H
A
N
G
T
D
V
G
F
D
L
H
G
S
Zebra Danio
Brachydanio rerio
NP_001074462
537
57239
Y272
G
R
K
T
F
S
N
Y
R
N
D
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175528
491
52555
S226
G
G
L
I
D
S
T
S
P
E
D
D
F
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23
70.4
67.3
N.A.
93
70.1
N.A.
68.1
40.6
48.7
27
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
36.1
70.4
70.1
N.A.
93.9
70.2
N.A.
72.5
48.2
56.7
41.2
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
0
6.6
6.6
N.A.
100
6.6
N.A.
6.6
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
33.3
33.3
N.A.
100
33.3
N.A.
20
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
28
10
0
0
10
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
10
0
19
0
10
19
28
10
0
10
0
% D
% Glu:
28
10
10
0
10
0
0
0
0
10
0
19
28
0
0
% E
% Phe:
19
0
0
0
10
0
0
0
0
19
0
0
10
0
19
% F
% Gly:
19
10
0
0
10
0
0
0
46
0
0
0
10
19
0
% G
% His:
19
10
28
0
0
0
10
0
0
0
10
0
10
0
0
% H
% Ile:
0
0
0
64
0
0
0
10
0
0
0
28
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
19
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
10
0
0
0
10
0
28
0
% L
% Met:
0
28
0
0
0
37
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
10
10
0
37
0
0
10
10
37
% N
% Pro:
0
0
0
0
0
0
19
0
10
0
0
0
19
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
10
0
0
0
0
28
0
28
0
10
0
0
0
0
% R
% Ser:
0
0
0
10
10
28
10
28
0
10
0
19
10
10
28
% S
% Thr:
0
19
0
10
0
28
10
28
0
0
0
19
10
0
10
% T
% Val:
0
10
0
10
19
0
0
10
0
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
0
10
0
0
28
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _