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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB6
All Species:
15.15
Human Site:
S970
Identified Species:
47.62
UniProt:
Q5THR3
Number Species:
7
Phosphosite Substitution
Charge Score:
0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5THR3
NP_073622.2
1501
172930
S970
M
D
R
H
Q
D
I
S
K
A
F
T
K
T
D
Chimpanzee
Pan troglodytes
XP_001171983
1501
173024
S970
M
D
R
H
Q
D
I
S
K
A
F
T
K
T
D
Rhesus Macaque
Macaca mulatta
XP_001108922
1501
172784
S970
V
D
C
Y
Q
D
I
S
K
A
F
T
K
I
D
Dog
Lupus familis
XP_538339
1613
185452
S1081
K
D
H
Y
Q
D
I
S
K
A
L
T
K
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1E8
1516
175753
S987
M
N
H
Y
E
E
I
S
K
A
F
N
A
M
E
Rat
Rattus norvegicus
XP_001077962
1510
174652
E981
K
L
L
D
H
F
E
E
I
S
K
A
L
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920584
1032
117690
E536
T
L
S
M
I
E
R
E
E
K
A
H
E
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187908
1266
147689
D770
S
H
N
Y
L
V
D
D
D
T
L
E
Q
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
93.1
71.4
N.A.
65.4
65.6
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
99.3
96.4
81.2
N.A.
80.4
80.1
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
100
73.3
66.6
N.A.
40
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
73.3
N.A.
73.3
6.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
63
13
13
13
13
13
% A
% Cys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
50
0
13
0
50
13
13
13
0
0
0
0
0
50
% D
% Glu:
0
0
0
0
13
25
13
25
13
0
0
13
13
0
13
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
50
0
0
13
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
13
25
25
13
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
0
0
0
13
0
63
0
13
0
0
0
0
13
0
% I
% Lys:
25
0
0
0
0
0
0
0
63
13
13
0
50
0
0
% K
% Leu:
0
25
13
0
13
0
0
0
0
0
25
0
13
13
13
% L
% Met:
38
0
0
13
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
13
13
0
0
0
0
0
0
0
0
13
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
50
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
0
0
25
0
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
13
0
0
0
0
63
0
13
0
0
0
0
13
% S
% Thr:
13
0
0
0
0
0
0
0
0
13
0
50
0
25
0
% T
% Val:
13
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _