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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGEF3
All Species:
24.85
Human Site:
S842
Identified Species:
54.67
UniProt:
Q5TH69
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TH69
NP_065073.3
2177
240652
S842
M
A
S
A
A
T
E
S
P
F
A
Q
S
R
R
Chimpanzee
Pan troglodytes
XP_518767
2177
240619
S842
M
A
S
A
A
T
E
S
P
F
A
Q
S
R
R
Rhesus Macaque
Macaca mulatta
XP_001095348
2107
232862
P808
L
I
D
T
L
S
T
P
L
T
G
R
M
A
G
Dog
Lupus familis
XP_541124
2192
241439
S845
M
A
S
A
S
T
E
S
P
F
T
Q
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UGY8
2170
240072
S838
M
A
S
A
S
V
E
S
P
F
T
Q
S
R
R
Rat
Rattus norvegicus
XP_218665
2170
240113
S838
M
A
S
A
S
M
E
S
P
F
T
Q
S
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419718
2177
241948
S839
M
A
S
A
S
A
Q
S
P
L
S
Q
N
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921357
2181
240848
S854
I
R
K
A
S
S
Q
S
P
F
T
C
D
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096888
2070
230154
A819
K
R
T
L
R
V
K
A
K
A
N
K
S
N
G
Honey Bee
Apis mellifera
XP_392019
2181
244055
S827
K
A
A
C
T
E
Q
S
I
S
K
I
T
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193250
1550
170185
L321
G
S
A
K
G
G
L
L
S
V
A
K
A
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.7
93.1
N.A.
92.8
92
N.A.
N.A.
84.8
N.A.
73.2
N.A.
22.8
32.4
N.A.
20.3
Protein Similarity:
100
99.9
96.2
96.1
N.A.
96
95.8
N.A.
N.A.
92.4
N.A.
84.1
N.A.
41.4
52.6
N.A.
35.8
P-Site Identity:
100
100
0
80
N.A.
80
73.3
N.A.
N.A.
46.6
N.A.
26.6
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
100
20
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
60
N.A.
33.3
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
64
19
64
19
10
0
10
0
10
28
0
10
19
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
10
46
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
10
0
0
0
0
10
0
10
0
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
19
0
10
10
0
0
10
0
10
0
10
19
0
10
28
% K
% Leu:
10
0
0
10
10
0
10
10
10
10
0
0
0
0
0
% L
% Met:
55
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
10
% N
% Pro:
0
0
0
0
0
0
0
10
64
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
28
0
0
0
0
55
0
10
0
% Q
% Arg:
0
19
0
0
10
0
0
0
0
0
0
10
0
55
37
% R
% Ser:
0
10
55
0
46
19
0
73
10
10
10
0
46
0
0
% S
% Thr:
0
0
10
10
10
28
10
0
0
10
37
0
10
0
10
% T
% Val:
0
0
0
0
0
19
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _