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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGEF3
All Species:
12.42
Human Site:
S1951
Identified Species:
27.33
UniProt:
Q5TH69
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TH69
NP_065073.3
2177
240652
S1951
Q
S
E
S
S
T
P
S
T
G
G
F
S
G
K
Chimpanzee
Pan troglodytes
XP_518767
2177
240619
S1951
Q
S
E
S
S
T
P
S
T
G
G
F
S
G
K
Rhesus Macaque
Macaca mulatta
XP_001095348
2107
232862
T1881
S
E
S
S
T
P
S
T
G
G
F
S
G
K
E
Dog
Lupus familis
XP_541124
2192
241439
E1966
S
G
K
D
T
P
S
E
D
D
R
S
Q
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UGY8
2170
240072
T1944
S
F
Q
S
E
S
S
T
P
S
T
G
G
F
S
Rat
Rattus norvegicus
XP_218665
2170
240113
T1944
S
F
Q
S
E
S
S
T
P
S
T
G
G
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419718
2177
241948
S1950
H
S
E
T
S
T
P
S
T
G
G
Q
S
G
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921357
2181
240848
E1952
F
L
P
L
F
N
S
E
T
S
T
P
S
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096888
2070
230154
N1857
N
L
G
P
E
D
L
N
F
I
L
E
S
C
S
Honey Bee
Apis mellifera
XP_392019
2181
244055
G1951
E
L
K
A
T
K
G
G
G
V
T
Y
D
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193250
1550
170185
E1339
D
D
K
D
D
D
K
E
R
E
A
N
G
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.7
93.1
N.A.
92.8
92
N.A.
N.A.
84.8
N.A.
73.2
N.A.
22.8
32.4
N.A.
20.3
Protein Similarity:
100
99.9
96.2
96.1
N.A.
96
95.8
N.A.
N.A.
92.4
N.A.
84.1
N.A.
41.4
52.6
N.A.
35.8
P-Site Identity:
100
100
13.3
0
N.A.
6.6
6.6
N.A.
N.A.
80
N.A.
13.3
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
33.3
20
N.A.
26.6
26.6
N.A.
N.A.
86.6
N.A.
13.3
N.A.
13.3
33.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
10
0
19
10
19
0
0
10
10
0
0
10
0
0
% D
% Glu:
10
10
28
0
28
0
0
28
0
10
0
10
0
19
10
% E
% Phe:
10
19
0
0
10
0
0
0
10
0
10
19
0
19
0
% F
% Gly:
0
10
10
0
0
0
10
10
19
37
28
19
37
28
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
28
0
0
10
10
0
0
0
0
0
0
10
28
% K
% Leu:
0
28
0
10
0
0
10
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% N
% Pro:
0
0
10
10
0
19
28
0
19
0
0
10
0
0
0
% P
% Gln:
19
0
19
0
0
0
0
0
0
0
0
10
10
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% R
% Ser:
37
28
10
46
28
19
46
28
0
28
0
19
46
0
28
% S
% Thr:
0
0
0
10
28
28
0
28
37
0
37
0
0
10
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _