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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC1A
All Species:
24.85
Human Site:
Y268
Identified Species:
60.74
UniProt:
Q5TB30
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TB30
NP_001107592.1
784
89358
Y268
N
D
M
N
N
P
T
Y
V
G
F
E
R
D
V
Chimpanzee
Pan troglodytes
XP_001165122
784
89401
Y268
N
D
M
N
N
P
T
Y
V
G
F
E
R
D
V
Rhesus Macaque
Macaca mulatta
XP_001096281
784
89056
Y268
N
D
M
N
N
P
T
Y
V
G
F
E
R
D
V
Dog
Lupus familis
XP_537116
857
98077
Y314
N
D
L
N
N
P
T
Y
V
G
F
E
R
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG0
804
92183
Y269
N
D
T
N
N
L
T
Y
V
G
F
E
R
D
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512859
866
98552
V323
D
M
S
Q
P
T
Y
V
G
F
E
R
D
V
F
Chicken
Gallus gallus
Q5ZLD2
529
61095
D51
F
K
A
S
E
A
V
D
C
L
H
E
L
L
G
Frog
Xenopus laevis
Q6ING4
806
92590
Y266
N
D
M
S
Q
A
T
Y
I
G
F
E
R
D
V
Zebra Danio
Brachydanio rerio
Q803Q4
800
90672
L261
D
S
D
Q
P
T
Y
L
G
F
E
R
D
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183893
1279
143476
Y308
I
D
S
D
L
P
S
Y
P
G
F
E
R
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
72.5
N.A.
74.1
N.A.
N.A.
58.3
30.3
48.5
44.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.6
97.9
80.5
N.A.
82
N.A.
N.A.
69.9
43.6
64.8
64.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
0
6.6
73.3
0
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
6.6
13.3
86.6
6.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
20
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
20
70
10
10
0
0
0
10
0
0
0
0
20
70
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
20
80
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
20
70
0
0
0
20
% F
% Gly:
0
0
0
0
0
0
0
0
20
70
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
10
10
0
10
0
10
0
0
10
10
0
% L
% Met:
0
10
40
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
50
50
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
50
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
20
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
20
70
0
0
% R
% Ser:
0
10
20
20
0
0
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
20
60
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
10
50
0
0
0
0
20
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _