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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC1A
All Species:
16.97
Human Site:
S131
Identified Species:
41.48
UniProt:
Q5TB30
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TB30
NP_001107592.1
784
89358
S131
K
N
N
I
E
N
F
S
K
D
K
D
S
I
F
Chimpanzee
Pan troglodytes
XP_001165122
784
89401
S131
K
N
N
I
E
N
F
S
K
D
K
D
S
I
F
Rhesus Macaque
Macaca mulatta
XP_001096281
784
89056
S131
R
N
N
I
E
N
F
S
K
D
K
D
S
I
F
Dog
Lupus familis
XP_537116
857
98077
S177
K
N
S
I
E
N
F
S
K
D
K
D
S
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG0
804
92183
S131
K
T
N
T
E
Y
F
S
K
D
K
D
G
I
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512859
866
98552
G187
K
N
S
A
E
S
T
G
K
E
K
E
S
L
F
Chicken
Gallus gallus
Q5ZLD2
529
61095
Frog
Xenopus laevis
Q6ING4
806
92590
F131
R
S
S
L
E
N
V
F
K
E
K
E
H
L
F
Zebra Danio
Brachydanio rerio
Q803Q4
800
90672
D131
R
K
S
L
S
M
M
D
R
E
S
F
F
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183893
1279
143476
A173
T
N
I
D
P
N
N
A
R
P
N
G
Q
G
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.9
72.5
N.A.
74.1
N.A.
N.A.
58.3
30.3
48.5
44.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.6
97.9
80.5
N.A.
82
N.A.
N.A.
69.9
43.6
64.8
64.5
N.A.
N.A.
N.A.
N.A.
38.7
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
N.A.
N.A.
46.6
0
33.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
73.3
N.A.
N.A.
80
0
80
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
50
0
50
0
0
0
% D
% Glu:
0
0
0
0
70
0
0
0
0
30
0
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
50
10
0
0
0
10
10
0
80
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
40
0
0
0
0
0
0
0
0
0
50
0
% I
% Lys:
50
10
0
0
0
0
0
0
70
0
70
0
0
10
0
% K
% Leu:
0
0
0
20
0
0
0
0
0
0
0
0
0
20
0
% L
% Met:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
60
40
0
0
60
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
30
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
10
40
0
10
10
0
50
0
0
10
0
50
0
0
% S
% Thr:
10
10
0
10
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _