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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WLS
All Species:
35.15
Human Site:
S418
Identified Species:
70.3
UniProt:
Q5T9L3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9L3
NP_001002292.1
541
62253
S418
Q
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
Chimpanzee
Pan troglodytes
XP_001164915
432
50033
K310
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
E
Rhesus Macaque
Macaca mulatta
XP_001095839
305
35297
S182
Q
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
Dog
Lupus familis
XP_853835
541
62057
S418
Q
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6DID7
541
62170
S418
Q
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
Rat
Rattus norvegicus
Q6P689
541
62184
S418
Q
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513709
541
62387
S418
Q
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
Chicken
Gallus gallus
Q5ZLR1
541
62119
S418
Q
S
S
L
P
A
M
S
K
A
R
R
L
H
Y
Frog
Xenopus laevis
Q66IZ4
541
61893
T418
Q
S
N
L
P
A
M
T
K
A
R
R
L
H
Y
Zebra Danio
Brachydanio rerio
NP_998311
542
62075
T419
R
S
C
L
P
A
M
T
K
A
R
R
L
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95ST2
594
67871
Q460
Y
T
K
A
F
F
F
Q
L
H
K
A
N
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785250
568
65141
A440
T
E
T
G
R
R
L
A
M
I
F
V
V
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
56.1
96.3
N.A.
96.1
95.7
N.A.
92.7
87.8
75
78
N.A.
40.9
N.A.
N.A.
46.4
Protein Similarity:
100
79.6
56.3
98.1
N.A.
97.9
98.1
N.A.
97
94.6
86.1
88.3
N.A.
60.6
N.A.
N.A.
63.2
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
93.3
80
73.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
13.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
75
0
9
0
25
0
9
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
0
0
9
9
9
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
9
75
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
9
75
0
9
0
0
0
0
% K
% Leu:
0
0
9
75
0
0
9
0
9
0
0
9
75
9
0
% L
% Met:
0
0
0
0
0
9
75
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
75
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
67
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
9
9
0
0
0
9
84
75
0
0
0
% R
% Ser:
9
84
59
0
0
0
9
59
0
0
0
0
0
0
9
% S
% Thr:
9
9
9
0
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
50
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _