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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACBD5
All Species:
9.7
Human Site:
T181
Identified Species:
21.33
UniProt:
Q5T8D3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T8D3
NP_001035938.1
534
60092
T181
L
G
N
V
L
T
S
T
P
N
A
K
T
V
N
Chimpanzee
Pan troglodytes
XP_507712
501
56067
E174
S
E
E
E
E
A
Q
E
E
V
K
G
A
E
Q
Rhesus Macaque
Macaca mulatta
XP_001115247
302
34300
Dog
Lupus familis
XP_848880
526
59330
T184
L
G
N
V
L
T
S
T
P
N
A
K
T
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5XG73
508
56595
S184
A
V
N
G
K
A
E
S
S
D
S
G
A
E
S
Rat
Rattus norvegicus
A0FKI7
506
56764
S184
A
V
N
G
K
A
E
S
S
D
S
G
A
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506917
496
55670
E171
G
A
E
S
E
E
E
E
A
L
E
E
V
K
Q
Chicken
Gallus gallus
Q5ZHQ6
492
54436
V172
E
K
E
L
Q
Q
N
V
K
D
C
K
S
P
K
Frog
Xenopus laevis
Q641E3
467
51356
S156
S
S
D
S
G
A
E
S
D
E
E
Q
A
A
A
Zebra Danio
Brachydanio rerio
Q502L1
501
55471
S172
A
E
T
L
K
V
K
S
I
D
L
E
D
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122639
288
32920
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
27.1
88.9
N.A.
78.6
77.9
N.A.
69.2
58.4
46.6
41
N.A.
N.A.
26.7
N.A.
N.A.
Protein Similarity:
100
93.8
38.9
93.4
N.A.
85.2
84.8
N.A.
78.6
70
60.8
59.9
N.A.
N.A.
39.1
N.A.
N.A.
P-Site Identity:
100
0
0
100
N.A.
6.6
6.6
N.A.
0
6.6
0
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
0
0
100
N.A.
33.3
33.3
N.A.
6.6
33.3
20
26.6
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
0
0
0
37
0
0
10
0
19
0
37
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
10
37
0
0
10
0
0
% D
% Glu:
10
19
28
10
19
10
37
19
10
10
19
19
0
28
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
19
0
19
10
0
0
0
0
0
0
28
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
28
0
10
0
10
0
10
28
0
10
10
% K
% Leu:
19
0
0
19
19
0
0
0
0
10
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
37
0
0
0
10
0
0
19
0
0
0
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
19
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
10
10
0
0
0
0
10
0
0
19
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
19
10
0
19
0
0
19
37
19
0
19
0
10
0
19
% S
% Thr:
0
0
10
0
0
19
0
19
0
0
0
0
19
0
0
% T
% Val:
0
19
0
19
0
10
0
10
0
10
0
0
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _