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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPRC6A
All Species:
14.85
Human Site:
Y406
Identified Species:
36.3
UniProt:
Q5T6X5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T6X5
NP_683766.2
926
104753
Y406
R
N
D
F
L
W
D
Y
A
E
P
G
L
I
H
Chimpanzee
Pan troglodytes
Q717C2
852
93438
S352
A
A
D
P
A
F
C
S
A
L
G
E
R
E
Q
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
R339
I
P
G
F
S
E
F
R
V
R
D
P
Q
A
G
Dog
Lupus familis
XP_541212
928
104506
Y406
R
N
D
F
L
W
D
Y
T
E
P
G
P
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Z6
928
104195
Y406
R
N
D
F
L
W
H
Y
T
E
P
G
L
I
Y
Rat
Rattus norvegicus
Q70VB1
928
104335
Y406
R
N
D
F
L
W
H
Y
T
E
P
G
L
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515899
1088
120096
Y411
V
E
T
P
Y
L
D
Y
T
H
L
R
I
S
Y
Chicken
Gallus gallus
XP_426177
996
111550
N403
R
D
D
F
L
N
A
N
I
E
P
G
F
I
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
F363
N
N
S
F
L
K
E
F
L
K
L
N
A
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
Y412
R
L
S
E
K
V
G
Y
E
Q
E
S
K
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.2
24.6
86.9
N.A.
80
80
N.A.
30.5
58.2
N.A.
41.7
N.A.
24.8
N.A.
N.A.
N.A.
Protein Similarity:
100
47
43.8
92.3
N.A.
87.2
87.5
N.A.
48.3
71.4
N.A.
60.2
N.A.
44.9
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
80
N.A.
80
86.6
N.A.
13.3
60
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
6.6
86.6
N.A.
86.6
86.6
N.A.
26.6
66.6
N.A.
46.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
10
0
20
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
60
0
0
0
30
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
0
10
0
10
10
0
10
50
10
10
0
10
0
% E
% Phe:
0
0
0
70
0
10
10
10
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
0
0
10
50
0
10
10
% G
% His:
0
0
0
0
0
0
20
0
0
10
0
0
0
0
40
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
10
40
0
% I
% Lys:
0
0
0
0
10
10
0
0
0
10
0
0
10
0
0
% K
% Leu:
0
10
0
0
60
10
0
0
10
10
20
0
30
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
50
0
0
0
10
0
10
0
0
0
10
0
0
10
% N
% Pro:
0
10
0
20
0
0
0
0
0
0
50
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
20
% Q
% Arg:
60
0
0
0
0
0
0
10
0
10
0
10
10
0
0
% R
% Ser:
0
0
20
0
10
0
0
10
0
0
0
10
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
40
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
60
0
0
0
0
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _