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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKR1CL1
All Species:
12.12
Human Site:
T76
Identified Species:
66.67
UniProt:
Q5T2L2
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T2L2
NP_001344
129
14588
T76
W
E
K
I
A
D
G
T
V
K
R
E
E
I
F
Chimpanzee
Pan troglodytes
XP_001154113
303
34402
P73
R
E
K
I
A
D
G
P
V
K
R
E
D
I
F
Rhesus Macaque
Macaca mulatta
XP_001118627
325
36982
T75
W
E
K
I
A
D
G
T
V
K
R
E
D
I
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70694
323
37029
T73
R
S
K
I
A
D
G
T
V
K
R
E
D
I
F
Rat
Rattus norvegicus
P51652
323
37281
T73
V
S
K
I
E
D
G
T
V
K
R
E
D
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33
34.7
N.A.
N.A.
28.1
24.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
38.2
37.2
N.A.
N.A.
33.7
30.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
93.3
N.A.
N.A.
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
N.A.
N.A.
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
100
0
0
0
0
0
0
80
0
0
% D
% Glu:
0
60
0
0
20
0
0
0
0
0
0
100
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
0
0
0
0
0
0
0
0
100
0
% I
% Lys:
0
0
100
0
0
0
0
0
0
100
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
40
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% R
% Ser:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% V
% Trp:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _