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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
25.76
Human Site:
S221
Identified Species:
37.78
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
S221
L
N
H
N
L
K
K
S
G
Y
E
V
P
T
P
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
S221
L
N
H
N
L
K
K
S
G
Y
E
V
P
T
P
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
Dog
Lupus familis
XP_537128
620
68704
S222
L
N
H
N
L
K
T
S
G
Y
E
V
P
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
S221
L
N
Q
N
L
K
K
S
G
Y
E
V
P
T
P
Rat
Rattus norvegicus
Q66HG7
589
65047
S221
L
N
Q
N
L
K
K
S
G
Y
E
V
P
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
S195
L
R
L
Q
L
G
I
S
V
Q
G
Q
G
V
S
Chicken
Gallus gallus
XP_422189
625
69278
S227
L
N
S
N
L
K
N
S
G
Y
E
V
P
T
P
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
H358
V
L
N
A
L
K
K
H
N
Y
E
K
P
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
S263
I
I
D
N
V
N
K
S
G
Y
K
I
P
T
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
G77
A
K
N
L
V
R
R
G
I
Q
T
T
A
P
K
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
P181
K
T
A
S
F
L
V
P
V
V
S
R
C
A
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
A162
D
T
G
S
G
K
T
A
S
F
L
V
P
I
I
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
G206
Q
T
G
S
G
K
T
G
G
F
L
F
P
L
F
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
V311
L
L
D
I
V
K
N
V
G
Y
D
E
P
T
P
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
20
86.6
0
53.3
N.A.
53.3
N.A.
N.A.
0
P-Site Similarity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
20
86.6
0
66.6
N.A.
80
N.A.
N.A.
26.6
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
0
N.A.
N.A.
20
20
46.6
P-Site Similarity:
6.6
N.A.
N.A.
40
33.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
0
0
7
0
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
0
13
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
44
7
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
13
0
7
0
0
7
% F
% Gly:
0
0
13
0
13
7
0
13
57
0
7
0
7
0
0
% G
% His:
0
0
19
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
0
7
0
7
0
0
7
0
7
7
% I
% Lys:
7
7
0
0
0
63
38
0
0
0
7
7
0
0
7
% K
% Leu:
50
13
7
7
50
7
0
0
0
0
13
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
38
13
44
0
7
13
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
69
7
57
% P
% Gln:
7
0
13
7
0
0
0
0
0
13
0
7
0
0
0
% Q
% Arg:
0
7
0
0
0
7
7
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
7
19
0
0
0
50
7
0
7
0
0
0
7
% S
% Thr:
0
19
0
0
0
0
19
0
0
0
7
7
0
57
7
% T
% Val:
7
0
0
0
19
0
7
7
13
7
0
44
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
57
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _