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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP15
All Species:
17.88
Human Site:
S940
Identified Species:
43.7
UniProt:
Q5T1M5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1M5
NP_056073.1
1219
133630
S940
E
Q
E
K
E
E
S
S
S
E
E
E
E
E
K
Chimpanzee
Pan troglodytes
XP_520196
1314
142629
S1035
E
Q
E
K
E
E
S
S
S
E
E
E
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001098655
1299
142252
S1018
E
Q
E
K
E
E
S
S
S
S
E
E
E
E
E
Dog
Lupus familis
XP_538799
1347
147406
S1081
E
Q
D
K
G
Q
S
S
S
E
E
E
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9Q6
1216
132942
E935
Q
E
E
E
E
E
E
E
E
E
E
E
E
E
K
Rat
Rattus norvegicus
XP_342847
1215
133044
S938
E
E
E
Q
G
E
C
S
S
E
E
E
K
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506981
1181
129059
L904
Y
E
Q
R
I
Q
E
L
E
E
Q
K
A
L
G
Chicken
Gallus gallus
XP_415541
1169
127681
V904
E
T
Y
S
G
R
M
V
L
G
V
V
M
N
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340227
782
87845
T519
H
F
S
F
G
L
A
T
V
S
L
E
T
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789663
743
84695
D480
R
Q
Q
L
K
D
N
D
N
K
Y
T
E
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
90.9
75.8
N.A.
79.9
79.2
N.A.
66
56.5
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
86.9
92.2
81.3
N.A.
86.9
86.5
N.A.
75.5
69.9
N.A.
42.9
N.A.
N.A.
N.A.
N.A.
37.4
P-Site Identity:
100
100
86.6
73.3
N.A.
60
60
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
86.6
N.A.
46.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% D
% Glu:
60
30
50
10
40
50
20
10
20
60
60
70
60
60
30
% E
% Phe:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
40
0
0
0
0
10
0
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
40
10
0
0
0
0
10
0
10
10
0
30
% K
% Leu:
0
0
0
10
0
10
0
10
10
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% M
% Asn:
0
0
0
0
0
0
10
0
10
0
0
0
0
20
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
50
20
10
0
20
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
0
0
40
50
50
20
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
10
10
0
10
% T
% Val:
0
0
0
0
0
0
0
10
10
0
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _