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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP15
All Species:
17.27
Human Site:
S750
Identified Species:
42.22
UniProt:
Q5T1M5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1M5
NP_056073.1
1219
133630
S750
L
S
E
R
K
K
K
S
A
Q
E
R
S
Q
A
Chimpanzee
Pan troglodytes
XP_520196
1314
142629
L847
V
T
S
L
E
E
E
L
T
D
L
R
V
E
K
Rhesus Macaque
Macaca mulatta
XP_001098655
1299
142252
S828
L
S
E
R
K
K
K
S
A
Q
E
R
S
Q
A
Dog
Lupus familis
XP_538799
1347
147406
S892
L
S
E
R
K
K
K
S
A
Q
E
R
C
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9Q6
1216
132942
S748
L
S
E
R
K
K
K
S
A
Q
E
R
C
Q
A
Rat
Rattus norvegicus
XP_342847
1215
133044
S750
L
S
E
R
K
K
K
S
A
Q
E
R
C
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506981
1181
129059
E717
Q
L
S
E
T
R
K
E
A
E
L
H
G
S
Q
Chicken
Gallus gallus
XP_415541
1169
127681
I718
R
K
H
L
D
M
K
I
S
A
L
E
E
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340227
782
87845
V333
D
Q
A
P
D
G
K
V
E
P
K
S
E
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789663
743
84695
G294
D
T
C
I
Y
G
N
G
R
E
S
K
N
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
90.9
75.8
N.A.
79.9
79.2
N.A.
66
56.5
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
86.9
92.2
81.3
N.A.
86.9
86.5
N.A.
75.5
69.9
N.A.
42.9
N.A.
N.A.
N.A.
N.A.
37.4
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
13.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
46.6
100
93.3
N.A.
93.3
93.3
N.A.
26.6
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
60
10
0
0
0
0
50
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
30
10
0
% C
% Asp:
20
0
0
0
20
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
50
10
10
10
10
10
10
20
50
10
20
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
20
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
50
50
80
0
0
0
10
10
0
0
10
% K
% Leu:
50
10
0
20
0
0
0
10
0
0
30
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
50
0
0
0
50
20
% Q
% Arg:
10
0
0
50
0
10
0
0
10
0
0
60
0
10
0
% R
% Ser:
0
50
20
0
0
0
0
50
10
0
10
10
20
10
0
% S
% Thr:
0
20
0
0
10
0
0
0
10
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _