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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP15
All Species:
8.48
Human Site:
S1155
Identified Species:
20.74
UniProt:
Q5T1M5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1M5
NP_056073.1
1219
133630
S1155
A
G
A
A
L
R
P
S
H
H
S
Q
R
S
S
Chimpanzee
Pan troglodytes
XP_520196
1314
142629
S1250
A
G
A
A
L
R
P
S
H
H
S
Q
R
S
S
Rhesus Macaque
Macaca mulatta
XP_001098655
1299
142252
S1235
A
G
A
A
L
R
S
S
H
H
S
Q
H
S
S
Dog
Lupus familis
XP_538799
1347
147406
E1295
H
A
S
L
S
G
D
E
D
D
E
L
F
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9Q6
1216
132942
N1150
A
G
T
S
L
R
H
N
Q
D
S
Q
H
C
S
Rat
Rattus norvegicus
XP_342847
1215
133044
Q1152
G
A
S
P
R
H
S
Q
D
S
Q
H
C
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506981
1181
129059
E1117
G
S
K
S
G
Q
E
E
E
Q
Q
Q
S
S
G
Chicken
Gallus gallus
XP_415541
1169
127681
L1116
G
G
L
E
P
P
P
L
S
S
E
G
E
N
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340227
782
87845
K731
H
S
T
E
A
L
M
K
Q
V
C
V
C
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789663
743
84695
A692
S
S
A
T
I
A
P
A
P
T
N
I
V
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
90.9
75.8
N.A.
79.9
79.2
N.A.
66
56.5
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
86.9
92.2
81.3
N.A.
86.9
86.5
N.A.
75.5
69.9
N.A.
42.9
N.A.
N.A.
N.A.
N.A.
37.4
P-Site Identity:
100
100
86.6
0
N.A.
46.6
6.6
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
6.6
N.A.
60
13.3
N.A.
26.6
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
20
40
30
10
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
20
10
20
% C
% Asp:
0
0
0
0
0
0
10
0
20
20
0
0
0
10
0
% D
% Glu:
0
0
0
20
0
0
10
20
10
0
20
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
30
50
0
0
10
10
0
0
0
0
0
10
0
0
20
% G
% His:
20
0
0
0
0
10
10
0
30
30
0
10
20
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% K
% Leu:
0
0
10
10
40
10
0
10
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
10
10
10
40
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
10
20
10
20
50
0
0
0
% Q
% Arg:
0
0
0
0
10
40
0
0
0
0
0
0
20
0
0
% R
% Ser:
10
30
20
20
10
0
20
30
10
20
40
0
10
50
40
% S
% Thr:
0
0
20
10
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _