KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C1orf125
All Species:
13.64
Human Site:
T380
Identified Species:
37.5
UniProt:
Q5T1B0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1B0
NP_653297.3
1012
118027
T380
E
E
Y
H
D
L
Y
T
L
Q
R
E
R
M
E
Chimpanzee
Pan troglodytes
XP_001157385
1012
117924
T380
E
E
Y
H
D
L
Y
T
L
Q
R
E
R
M
E
Rhesus Macaque
Macaca mulatta
XP_001115386
1012
118031
T379
E
E
Y
H
D
L
Y
T
L
Q
R
E
R
M
E
Dog
Lupus familis
XP_537173
1042
120820
T381
E
E
Y
H
D
L
Y
T
L
Q
R
E
R
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UZ57
424
49788
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515722
1063
122237
E386
E
D
Y
R
G
L
Y
E
L
Q
R
G
R
L
E
Chicken
Gallus gallus
XP_422266
1096
125171
I372
A
C
D
L
A
L
K
I
I
E
R
N
Q
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082846
1007
115519
E371
A
E
Y
H
E
L
Y
E
L
Q
R
K
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783451
1165
129085
E380
G
E
Y
H
E
L
Y
E
L
Q
R
R
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.8
74.2
N.A.
30.3
N.A.
N.A.
47.7
35.9
N.A.
36.1
N.A.
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
99.8
97.2
83.9
N.A.
36.8
N.A.
N.A.
66.2
55.8
N.A.
56.8
N.A.
N.A.
N.A.
N.A.
50.8
P-Site Identity:
100
100
100
100
N.A.
0
N.A.
N.A.
60
13.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
0
N.A.
N.A.
73.3
40
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
45
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
56
67
0
0
23
0
0
34
0
12
0
45
0
0
78
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% K
% Leu:
0
0
0
12
0
89
0
0
78
0
0
0
0
45
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
45
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
78
0
0
12
0
0
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
89
12
78
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
78
0
0
0
78
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _