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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C1orf125
All Species:
10
Human Site:
S644
Identified Species:
27.5
UniProt:
Q5T1B0
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1B0
NP_653297.3
1012
118027
S644
E
K
I
N
E
M
K
S
H
L
D
I
L
L
N
Chimpanzee
Pan troglodytes
XP_001157385
1012
117924
S644
E
K
I
N
E
M
K
S
H
L
D
I
L
L
N
Rhesus Macaque
Macaca mulatta
XP_001115386
1012
118031
L643
E
K
I
N
E
M
K
L
Q
L
D
L
L
L
N
Dog
Lupus familis
XP_537173
1042
120820
S647
E
K
V
N
E
M
K
S
Q
L
D
A
A
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3UZ57
424
49788
T122
K
N
V
I
E
E
L
T
R
E
L
C
L
V
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515722
1063
122237
E655
E
M
L
S
Q
L
N
E
L
L
A
T
V
G
S
Chicken
Gallus gallus
XP_422266
1096
125171
A609
S
W
L
A
Q
V
D
A
L
M
S
V
I
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082846
1007
115519
E643
S
L
V
N
L
S
E
E
A
L
L
L
V
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783451
1165
129085
E658
D
W
I
R
T
I
N
E
V
E
Q
N
I
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.8
74.2
N.A.
30.3
N.A.
N.A.
47.7
35.9
N.A.
36.1
N.A.
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
99.8
97.2
83.9
N.A.
36.8
N.A.
N.A.
66.2
55.8
N.A.
56.8
N.A.
N.A.
N.A.
N.A.
50.8
P-Site Identity:
100
100
80
73.3
N.A.
13.3
N.A.
N.A.
13.3
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
86.6
80
N.A.
40
N.A.
N.A.
53.3
53.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
12
12
0
12
12
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
12
0
0
0
0
0
12
0
0
0
45
0
0
12
0
% D
% Glu:
56
0
0
0
56
12
12
34
0
23
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% G
% His:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% H
% Ile:
0
0
45
12
0
12
0
0
0
0
0
23
23
0
0
% I
% Lys:
12
45
0
0
0
0
45
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
23
0
12
12
12
12
23
67
23
23
45
45
0
% L
% Met:
0
12
0
0
0
45
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
12
0
56
0
0
23
0
0
0
0
12
0
0
45
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
23
0
0
0
23
0
12
0
0
0
12
% Q
% Arg:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
23
0
0
12
0
12
0
34
0
0
12
0
0
0
45
% S
% Thr:
0
0
0
0
12
0
0
12
0
0
0
12
0
0
0
% T
% Val:
0
0
34
0
0
12
0
0
12
0
0
12
23
12
0
% V
% Trp:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _