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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CC2D1B
All Species:
8.18
Human Site:
S273
Identified Species:
18
UniProt:
Q5T0F9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T0F9
NP_115825.1
858
94224
S273
G
I
S
A
Q
P
V
S
D
L
D
P
D
P
R
Chimpanzee
Pan troglodytes
XP_513407
858
94137
S273
G
I
S
A
Q
P
V
S
D
L
D
P
D
P
R
Rhesus Macaque
Macaca mulatta
XP_001105514
798
87629
S257
A
L
E
S
D
N
P
S
Q
P
E
T
S
L
P
Dog
Lupus familis
XP_539614
909
98881
P321
S
L
G
I
S
A
P
P
D
S
D
P
D
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRN9
848
93073
P270
L
P
A
I
A
P
L
P
D
S
D
P
D
P
Q
Rat
Rattus norvegicus
Q5FVK6
850
93515
P272
L
P
A
V
A
A
L
P
D
S
D
P
D
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PF54
864
95663
S287
V
E
K
T
H
V
A
S
E
N
D
T
D
S
K
Zebra Danio
Brachydanio rerio
XP_692169
859
94055
F290
A
E
K
H
L
V
D
F
P
V
G
Q
P
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKJ9
816
89019
T253
P
T
T
S
V
A
P
T
S
P
P
N
P
L
V
Honey Bee
Apis mellifera
XP_396955
792
89420
K229
V
E
K
P
T
S
T
K
N
I
D
E
E
A
L
Nematode Worm
Caenorhab. elegans
Q9U2M8
792
85482
A230
I
R
Q
A
A
H
A
A
E
S
S
P
P
P
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
89.6
80.3
N.A.
80.7
80.6
N.A.
N.A.
N.A.
54.1
49.7
N.A.
34.2
27.9
24.4
N.A.
Protein Similarity:
100
99.8
91.1
85.5
N.A.
87.5
87.7
N.A.
N.A.
N.A.
69.7
66
N.A.
55.2
50
42.1
N.A.
P-Site Identity:
100
100
6.6
40
N.A.
40
33.3
N.A.
N.A.
N.A.
20
0
N.A.
0
6.6
20
N.A.
P-Site Similarity:
100
100
26.6
46.6
N.A.
60
53.3
N.A.
N.A.
N.A.
33.3
13.3
N.A.
20
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
19
28
28
28
19
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
46
0
64
0
55
0
0
% D
% Glu:
0
28
10
0
0
0
0
0
19
0
10
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
19
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
19
0
19
0
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
0
0
28
0
0
0
0
10
0
0
0
0
0
0
19
% K
% Leu:
19
19
0
0
10
0
19
0
0
19
0
0
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
10
0
10
0
0
0
% N
% Pro:
10
19
0
10
0
28
28
28
10
19
10
55
28
55
10
% P
% Gln:
0
0
10
0
19
0
0
0
10
0
0
10
0
0
19
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
28
% R
% Ser:
10
0
19
19
10
10
0
37
10
37
10
0
10
10
0
% S
% Thr:
0
10
10
10
10
0
10
10
0
0
0
19
0
10
0
% T
% Val:
19
0
0
10
10
19
19
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _