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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CC2D1B All Species: 11.52
Human Site: S241 Identified Species: 25.33
UniProt: Q5T0F9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T0F9 NP_115825.1 858 94224 S241 P Q E P A N R S P E T D P P A
Chimpanzee Pan troglodytes XP_513407 858 94137 S241 P Q E P A N R S P E T D P P A
Rhesus Macaque Macaca mulatta XP_001105514 798 87629 A225 D E I P P P V A L G K R P L V
Dog Lupus familis XP_539614 909 98881 A289 A A D R N P E A E A D A P A P
Cat Felis silvestris
Mouse Mus musculus Q8BRN9 848 93073 I238 P A P Q E R A I K N P E I D S
Rat Rattus norvegicus Q5FVK6 850 93515 S240 P A H Q E R P S K D S E I D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6PF54 864 95663 T255 L N D V P M E T T E A V T N L
Zebra Danio Brachydanio rerio XP_692169 859 94055 I258 V M D T E S N I R D E S S G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKJ9 816 89019 S221 A E E S P A P S T P A S P P P
Honey Bee Apis mellifera XP_396955 792 89420 T197 T N A K I L E T K K T E S T E
Nematode Worm Caenorhab. elegans Q9U2M8 792 85482 S198 P V A P P N F S S A A A E P L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 89.6 80.3 N.A. 80.7 80.6 N.A. N.A. N.A. 54.1 49.7 N.A. 34.2 27.9 24.4 N.A.
Protein Similarity: 100 99.8 91.1 85.5 N.A. 87.5 87.7 N.A. N.A. N.A. 69.7 66 N.A. 55.2 50 42.1 N.A.
P-Site Identity: 100 100 13.3 6.6 N.A. 6.6 13.3 N.A. N.A. N.A. 6.6 0 N.A. 26.6 6.6 33.3 N.A.
P-Site Similarity: 100 100 26.6 20 N.A. 20 40 N.A. N.A. N.A. 20 20 N.A. 33.3 26.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 28 19 0 19 10 10 19 0 19 28 19 0 10 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 28 0 0 0 0 0 0 19 10 19 0 19 0 % D
% Glu: 0 19 28 0 28 0 28 0 10 28 10 28 10 0 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 10 0 0 19 0 0 0 0 19 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 28 10 10 0 0 0 0 % K
% Leu: 10 0 0 0 0 10 0 0 10 0 0 0 0 10 19 % L
% Met: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 0 0 10 28 10 0 0 10 0 0 0 10 0 % N
% Pro: 46 0 10 37 37 19 19 0 19 10 10 0 46 37 19 % P
% Gln: 0 19 0 19 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 19 19 0 10 0 0 10 0 0 0 % R
% Ser: 0 0 0 10 0 10 0 46 10 0 10 19 19 0 19 % S
% Thr: 10 0 0 10 0 0 0 19 19 0 28 0 10 10 0 % T
% Val: 10 10 0 10 0 0 10 0 0 0 0 10 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _