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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANEA
All Species:
21.21
Human Site:
Y381
Identified Species:
46.67
UniProt:
Q5SRI9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SRI9
NP_078917.2
462
53671
Y381
R
N
R
I
N
G
K
Y
Y
E
I
G
L
S
A
Chimpanzee
Pan troglodytes
XP_527453
577
66263
Y496
R
N
R
I
N
G
K
Y
Y
E
I
A
L
S
A
Rhesus Macaque
Macaca mulatta
XP_001096615
577
65849
Y496
R
N
R
I
N
G
K
Y
Y
E
I
A
L
S
A
Dog
Lupus familis
XP_539046
478
55693
Y397
R
N
R
I
N
G
K
Y
Y
E
T
A
L
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXH2
462
53165
Y381
R
N
R
V
N
G
K
Y
Y
E
V
G
L
S
A
Rat
Rattus norvegicus
Q5GF25
462
53398
Y381
R
N
R
I
N
G
K
Y
Y
E
V
G
L
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506704
456
52289
R375
P
W
N
N
H
N
T
R
N
R
V
N
G
K
Y
Chicken
Gallus gallus
XP_419831
457
52792
R376
P
W
N
N
H
N
T
R
N
R
V
N
G
K
Y
Frog
Xenopus laevis
Q6DE40
449
51843
N369
W
N
F
Q
N
T
R
N
R
I
N
G
K
Y
Y
Zebra Danio
Brachydanio rerio
Q1L8D2
442
50295
N362
W
N
N
H
N
T
R
N
R
V
N
G
R
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796542
491
57060
W409
V
D
T
R
V
R
P
W
N
K
M
N
T
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79
78.1
82.4
N.A.
85.5
85.5
N.A.
70.5
70.5
64.9
54.9
N.A.
N.A.
N.A.
N.A.
45.2
Protein Similarity:
100
79
79
89.3
N.A.
92.6
92.6
N.A.
81.1
80.5
79
73.5
N.A.
N.A.
N.A.
N.A.
63.1
P-Site Identity:
100
93.3
93.3
80
N.A.
86.6
93.3
N.A.
0
0
20
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
80
N.A.
100
100
N.A.
13.3
13.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
55
0
0
0
0
0
46
19
0
0
% G
% His:
0
0
0
10
19
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
46
0
0
0
0
0
10
28
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
55
0
0
10
0
0
10
28
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
73
28
19
73
19
0
19
28
0
19
28
0
0
0
% N
% Pro:
19
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
55
0
55
10
0
10
19
19
19
19
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% S
% Thr:
0
0
10
0
0
19
19
0
0
0
10
0
10
0
0
% T
% Val:
10
0
0
10
10
0
0
0
0
10
37
0
0
0
0
% V
% Trp:
19
19
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
55
0
0
0
0
19
37
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _