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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MANEA All Species: 22.73
Human Site: Y360 Identified Species: 50
UniProt: Q5SRI9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SRI9 NP_078917.2 462 53671 Y360 I P S V G P G Y I D T S I R P
Chimpanzee Pan troglodytes XP_527453 577 66263 Y475 I P S V G P G Y I D T S I R P
Rhesus Macaque Macaca mulatta XP_001096615 577 65849 Y475 I P S V G P G Y I D T S I R P
Dog Lupus familis XP_539046 478 55693 Y376 I P S V G P G Y I D T S I R P
Cat Felis silvestris
Mouse Mus musculus Q6NXH2 462 53165 Y360 I P S V G P G Y I D T S I R P
Rat Rattus norvegicus Q5GF25 462 53398 Y360 I P S V G P G Y I D T S I R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506704 456 52289 I354 D S N S L M F I P S V G P G Y
Chicken Gallus gallus XP_419831 457 52792 I355 D S N N L M F I P S V G P G Y
Frog Xenopus laevis Q6DE40 449 51843 P348 T N N L L F I P S V G P G Y I
Zebra Danio Brachydanio rerio Q1L8D2 442 50295 P341 K N N L L F V P S A G P G Y M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796542 491 57060 K388 L L A D F A Q K R D L L F V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79 78.1 82.4 N.A. 85.5 85.5 N.A. 70.5 70.5 64.9 54.9 N.A. N.A. N.A. N.A. 45.2
Protein Similarity: 100 79 79 89.3 N.A. 92.6 92.6 N.A. 81.1 80.5 79 73.5 N.A. N.A. N.A. N.A. 63.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 6.6 13.3 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 10 0 0 0 0 0 64 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 10 19 19 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 55 0 55 0 0 0 19 19 19 19 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 55 0 0 0 0 0 10 19 55 0 0 0 55 0 10 % I
% Lys: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 19 37 0 0 0 0 0 10 10 0 0 0 % L
% Met: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 19 37 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 55 0 0 0 55 0 19 19 0 0 19 19 0 64 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 55 0 % R
% Ser: 0 19 55 10 0 0 0 0 19 19 0 55 0 0 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 55 0 0 0 0 % T
% Val: 0 0 0 55 0 0 10 0 0 10 19 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 55 0 0 0 0 0 19 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _