KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MANEA
All Species:
20.91
Human Site:
T258
Identified Species:
46
UniProt:
Q5SRI9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SRI9
NP_078917.2
462
53671
T258
F
Y
R
Y
K
T
K
T
G
N
A
L
P
M
F
Chimpanzee
Pan troglodytes
XP_527453
577
66263
T373
F
Y
R
Y
K
T
K
T
G
N
A
L
P
M
F
Rhesus Macaque
Macaca mulatta
XP_001096615
577
65849
T373
F
Y
R
Y
K
T
K
T
G
N
A
L
P
M
F
Dog
Lupus familis
XP_539046
478
55693
T274
F
Y
R
Y
K
T
R
T
G
N
A
L
P
M
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6NXH2
462
53165
T258
F
Y
R
Y
K
T
R
T
G
H
S
L
P
M
F
Rat
Rattus norvegicus
Q5GF25
462
53398
M258
F
Y
R
Y
K
T
R
M
G
H
S
L
P
M
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506704
456
52289
F252
K
Y
G
S
H
P
A
F
Y
R
Q
K
T
N
S
Chicken
Gallus gallus
XP_419831
457
52792
F253
K
Y
G
A
H
P
A
F
Y
R
H
K
T
S
T
Frog
Xenopus laevis
Q6DE40
449
51843
Y246
Y
G
S
H
P
A
F
Y
K
Y
K
T
D
N
G
Zebra Danio
Brachydanio rerio
Q1L8D2
442
50295
Y239
Y
G
T
H
G
A
F
Y
R
F
K
S
S
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796542
491
57060
T286
D
V
R
Y
I
I
D
T
Y
G
M
H
P
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79
78.1
82.4
N.A.
85.5
85.5
N.A.
70.5
70.5
64.9
54.9
N.A.
N.A.
N.A.
N.A.
45.2
Protein Similarity:
100
79
79
89.3
N.A.
92.6
92.6
N.A.
81.1
80.5
79
73.5
N.A.
N.A.
N.A.
N.A.
63.1
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
6.6
6.6
0
0
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
6.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
19
19
0
0
0
37
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
55
0
0
0
0
0
19
19
0
10
0
0
0
0
64
% F
% Gly:
0
19
19
0
10
0
0
0
55
10
0
0
0
0
19
% G
% His:
0
0
0
19
19
0
0
0
0
19
10
10
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
0
0
55
0
28
0
10
0
19
19
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
55
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
37
0
0
0
19
0
% N
% Pro:
0
0
0
0
10
19
0
0
0
0
0
0
64
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
64
0
0
0
28
0
10
19
0
0
0
0
0
% R
% Ser:
0
0
10
10
0
0
0
0
0
0
19
10
10
10
10
% S
% Thr:
0
0
10
0
0
55
0
55
0
0
0
10
19
10
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
73
0
64
0
0
0
19
28
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _