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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC6
All Species:
16.36
Human Site:
T34
Identified Species:
30
UniProt:
Q5RKV6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5RKV6
NP_478126.1
272
28235
T34
A
P
G
T
R
D
P
T
R
L
R
P
V
Y
A
Chimpanzee
Pan troglodytes
XP_523406
272
28247
T34
A
P
G
T
R
D
P
T
R
L
R
P
V
Y
A
Rhesus Macaque
Macaca mulatta
XP_001101736
185
19058
E13
R
R
I
R
G
P
E
E
S
Q
P
P
Q
L
Y
Dog
Lupus familis
XP_546833
272
28271
T34
A
P
A
A
R
D
P
T
R
L
R
P
V
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW3
273
28352
T34
T
P
A
A
R
D
P
T
R
L
R
P
V
Y
A
Rat
Rattus norvegicus
XP_226471
312
32781
T74
T
P
A
A
R
D
P
T
R
L
R
P
V
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0I8
271
29438
G40
R
Q
G
V
R
G
N
G
D
V
R
P
V
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609618
246
27003
G38
G
V
F
E
Q
P
D
G
S
A
Y
M
E
Q
G
Honey Bee
Apis mellifera
XP_623498
273
30513
N44
R
N
D
K
R
S
N
N
E
M
R
K
I
F
L
Nematode Worm
Caenorhab. elegans
Q17533
240
26046
E39
A
E
G
S
C
Y
L
E
H
G
N
T
K
V
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328307
263
28041
H48
R
S
D
G
R
G
F
H
Q
C
R
S
A
F
F
Maize
Zea mays
NP_001168912
209
22466
P29
V
I
V
S
V
F
G
P
R
E
S
K
K
A
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46948
246
27542
S40
P
H
A
A
D
G
S
S
Y
M
E
Q
G
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
66.5
95.2
N.A.
91.5
80.4
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
30.8
35.9
26.1
N.A.
Protein Similarity:
100
99.6
66.5
95.5
N.A.
94.5
82.6
N.A.
N.A.
N.A.
N.A.
66.9
N.A.
46.6
56.7
42.2
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
40
N.A.
0
13.3
13.3
N.A.
P-Site Similarity:
100
100
6.6
86.6
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
6.6
33.3
20
N.A.
Percent
Protein Identity:
26.8
28.3
N.A.
N.A.
23.5
N.A.
Protein Similarity:
43.3
42.6
N.A.
N.A.
40.4
N.A.
P-Site Identity:
13.3
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
26.6
13.3
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
31
31
0
0
0
0
0
8
0
0
8
8
47
% A
% Cys:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
16
0
8
39
8
0
8
0
0
0
0
0
0
% D
% Glu:
0
8
0
8
0
0
8
16
8
8
8
0
8
0
0
% E
% Phe:
0
0
8
0
0
8
8
0
0
0
0
0
0
24
8
% F
% Gly:
8
0
31
8
8
24
8
16
0
8
0
0
8
0
8
% G
% His:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
16
16
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
39
0
0
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
16
0
8
0
0
8
% M
% Asn:
0
8
0
0
0
0
16
8
0
0
8
0
0
8
8
% N
% Pro:
8
39
0
0
0
16
39
8
0
0
8
54
0
0
0
% P
% Gln:
0
8
0
0
8
0
0
0
8
8
0
8
8
8
0
% Q
% Arg:
31
8
0
8
62
0
0
0
47
0
62
0
0
0
0
% R
% Ser:
0
8
0
16
0
8
8
8
16
0
8
8
0
0
0
% S
% Thr:
16
0
0
16
0
0
0
39
0
0
0
8
0
0
0
% T
% Val:
8
8
8
8
8
0
0
0
0
8
0
0
47
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
8
0
0
39
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _