KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC6
All Species:
18.18
Human Site:
S14
Identified Species:
33.33
UniProt:
Q5RKV6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5RKV6
NP_478126.1
272
28235
S14
R
I
R
G
P
E
E
S
Q
P
P
Q
L
Y
A
Chimpanzee
Pan troglodytes
XP_523406
272
28247
S14
R
I
R
G
P
E
E
S
Q
P
P
Q
L
Y
A
Rhesus Macaque
Macaca mulatta
XP_001101736
185
19058
Dog
Lupus familis
XP_546833
272
28271
S14
R
I
R
G
P
E
E
S
Q
P
P
Q
L
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTW3
273
28352
S14
R
I
R
G
P
E
E
S
Q
P
P
Q
L
Y
A
Rat
Rattus norvegicus
XP_226471
312
32781
S54
R
I
R
G
P
E
E
S
Q
P
P
Q
L
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6P0I8
271
29438
F20
E
S
Q
S
P
L
L
F
L
S
P
D
K
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609618
246
27003
R18
Q
G
L
R
L
D
G
R
R
P
H
E
L
R
R
Honey Bee
Apis mellifera
XP_623498
273
30513
N24
Y
Y
I
Y
S
N
L
N
K
K
S
D
K
I
K
Nematode Worm
Caenorhab. elegans
Q17533
240
26046
I19
D
G
R
R
P
A
Q
I
R
N
I
N
T
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328307
263
28041
R28
T
P
T
K
K
A
Q
R
P
P
F
F
T
D
S
Maize
Zea mays
NP_001168912
209
22466
A9
Q
T
G
P
T
T
A
A
S
G
S
A
Y
A
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P46948
246
27542
N20
R
L
D
G
R
R
W
N
E
L
R
R
F
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
66.5
95.2
N.A.
91.5
80.4
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
30.8
35.9
26.1
N.A.
Protein Similarity:
100
99.6
66.5
95.5
N.A.
94.5
82.6
N.A.
N.A.
N.A.
N.A.
66.9
N.A.
46.6
56.7
42.2
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
0
13.3
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
20
N.A.
40
13.3
26.6
N.A.
Percent
Protein Identity:
26.8
28.3
N.A.
N.A.
23.5
N.A.
Protein Similarity:
43.3
42.6
N.A.
N.A.
40.4
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
20
13.3
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
8
8
0
0
0
8
0
16
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
8
0
0
0
0
0
16
0
8
0
% D
% Glu:
8
0
0
0
0
39
39
0
8
0
0
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
8
8
0
0
% F
% Gly:
0
16
8
47
0
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
39
8
0
0
0
0
8
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
8
8
0
0
0
8
8
0
0
16
0
8
% K
% Leu:
0
8
8
0
8
8
16
0
8
8
0
0
47
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
16
0
8
0
8
0
0
0
% N
% Pro:
0
8
0
8
54
0
0
0
8
54
47
0
0
0
8
% P
% Gln:
16
0
8
0
0
0
16
0
39
0
0
39
0
0
0
% Q
% Arg:
47
0
47
16
8
8
0
16
16
0
8
8
0
16
8
% R
% Ser:
0
8
0
8
8
0
0
39
8
8
16
0
0
0
16
% S
% Thr:
8
8
8
0
8
8
0
0
0
0
0
0
16
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
0
0
0
0
0
0
0
8
39
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _