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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM75A2
All Species:
2.73
Human Site:
T875
Identified Species:
12
UniProt:
Q5RGS2
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5RGS2
NP_001035154.1
1347
148657
T875
S
L
R
K
Q
V
L
T
K
A
S
D
H
M
P
Chimpanzee
Pan troglodytes
XP_001169768
1272
140122
L811
D
H
M
P
E
S
L
L
A
S
S
P
A
C
K
Rhesus Macaque
Macaca mulatta
XP_001114434
793
86773
G366
A
P
P
A
A
Q
E
G
R
W
P
S
K
P
L
Dog
Lupus familis
XP_848290
1268
140791
R827
S
L
I
G
Q
E
D
R
Q
P
S
Q
S
L
T
Cat
Felis silvestris
Mouse
Mus musculus
NP_084323
1014
115816
S587
P
Q
N
L
L
L
V
S
S
P
S
C
K
R
A
Rat
Rattus norvegicus
NP_001008360
1048
119532
S621
Q
I
I
I
K
D
S
S
P
P
P
G
N
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.7
51.6
40.6
N.A.
28
29.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92
54.1
55.2
N.A.
42.4
43.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
26.6
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
13.3
40
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
17
17
0
0
0
17
17
0
0
17
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
17
0
17
0
% C
% Asp:
17
0
0
0
0
17
17
0
0
0
0
17
0
0
0
% D
% Glu:
0
0
0
0
17
17
17
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
17
0
0
0
17
0
0
0
% G
% His:
0
17
0
0
0
0
0
0
0
0
0
0
17
0
0
% H
% Ile:
0
17
34
17
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
17
0
0
0
17
0
0
0
34
0
17
% K
% Leu:
0
34
0
17
17
17
34
17
0
0
0
0
0
34
34
% L
% Met:
0
0
17
0
0
0
0
0
0
0
0
0
0
17
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
17
0
0
% N
% Pro:
17
17
17
17
0
0
0
0
17
50
34
17
0
17
17
% P
% Gln:
17
17
0
0
34
17
0
0
17
0
0
17
0
0
0
% Q
% Arg:
0
0
17
0
0
0
0
17
17
0
0
0
0
17
0
% R
% Ser:
34
0
0
0
0
17
17
34
17
17
67
17
17
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
17
% T
% Val:
0
0
0
0
0
17
17
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _