Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPDYA All Species: 13.94
Human Site: T224 Identified Species: 34.07
UniProt: Q5MJ70 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5MJ70 NP_001008779.1 313 36463 T224 L P R G P S A T P V D C S L C
Chimpanzee Pan troglodytes XP_515374 225 26070 P137 P R G P S A T P V D C S L C G
Rhesus Macaque Macaca mulatta XP_001102674 313 36653 T224 L P R G P S A T P V D C S L C
Dog Lupus familis XP_533235 197 22566 A109 T H S N L F L A L F L A N D M
Cat Felis silvestris
Mouse Mus musculus Q5IBH7 310 36038 S221 V H L P R G P S A T P V D C S
Rat Rattus norvegicus Q8R496 312 36205 T223 L P R G P S A T P V D C S L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509302 311 36120 T223 M P R G P N A T P E D C S L C
Chicken Gallus gallus
Frog Xenopus laevis Q9PU13 299 34670 R201 I H H S G A M R G Y L R N E D
Zebra Danio Brachydanio rerio NP_001006091 289 33220 L199 H H S G A Q R L Q Q N R E E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782631 266 30955 I178 M S L V P D H I I W K R D R M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.8 97.4 28.4 N.A. 83.3 85.9 N.A. 69.3 N.A. 39.6 49.8 N.A. N.A. N.A. N.A. 42.8
Protein Similarity: 100 71.8 98.7 38.6 N.A. 90 91 N.A. 80.8 N.A. 55.9 64.8 N.A. N.A. N.A. N.A. 59.4
P-Site Identity: 100 0 100 0 N.A. 0 100 N.A. 80 N.A. 0 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 6.6 100 6.6 N.A. 13.3 100 N.A. 93.3 N.A. 20 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 20 40 10 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 40 0 20 40 % C
% Asp: 0 0 0 0 0 10 0 0 0 10 40 0 20 10 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 10 20 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 50 10 10 0 0 10 0 0 0 0 0 10 % G
% His: 10 40 10 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 10 10 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 30 0 20 0 10 0 10 10 10 0 20 0 10 40 0 % L
% Met: 20 0 0 0 0 0 10 0 0 0 0 0 0 0 20 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 10 0 20 0 0 % N
% Pro: 10 40 0 20 50 0 10 10 40 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 10 10 0 0 0 0 0 % Q
% Arg: 0 10 40 0 10 0 10 10 0 0 0 30 0 10 0 % R
% Ser: 0 10 20 10 10 30 0 10 0 0 0 10 40 0 10 % S
% Thr: 10 0 0 0 0 0 10 40 0 10 0 0 0 0 0 % T
% Val: 10 0 0 10 0 0 0 0 10 30 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _