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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPDYA
All Species:
13.03
Human Site:
S290
Identified Species:
31.85
UniProt:
Q5MJ70
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5MJ70
NP_001008779.1
313
36463
S290
E
V
V
N
D
H
Q
S
N
K
G
K
K
T
N
Chimpanzee
Pan troglodytes
XP_515374
225
26070
N203
V
V
N
D
H
Q
S
N
K
G
K
K
T
N
F
Rhesus Macaque
Macaca mulatta
XP_001102674
313
36653
S290
Q
V
V
N
D
H
Q
S
N
K
G
K
K
T
N
Dog
Lupus familis
XP_533235
197
22566
H175
V
M
A
K
E
P
S
H
W
A
W
T
R
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5IBH7
310
36038
S287
Q
V
A
N
D
H
Q
S
N
K
E
N
E
T
N
Rat
Rattus norvegicus
Q8R496
312
36205
S289
Q
V
A
N
D
H
Q
S
K
K
E
N
E
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509302
311
36120
D289
V
P
Y
E
N
L
S
D
K
E
G
K
T
S
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PU13
299
34670
L267
L
L
M
L
S
P
E
L
L
L
D
P
E
C
T
Zebra Danio
Brachydanio rerio
NP_001006091
289
33220
Y265
K
A
Q
H
T
C
K
Y
K
P
I
A
G
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782631
266
30955
Q244
T
F
L
T
D
Y
P
Q
S
V
I
E
C
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.8
97.4
28.4
N.A.
83.3
85.9
N.A.
69.3
N.A.
39.6
49.8
N.A.
N.A.
N.A.
N.A.
42.8
Protein Similarity:
100
71.8
98.7
38.6
N.A.
90
91
N.A.
80.8
N.A.
55.9
64.8
N.A.
N.A.
N.A.
N.A.
59.4
P-Site Identity:
100
13.3
93.3
0
N.A.
66.6
60
N.A.
13.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
20
N.A.
80
73.3
N.A.
33.3
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
30
0
0
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
10
10
10
% C
% Asp:
0
0
0
10
50
0
0
10
0
0
10
0
0
0
10
% D
% Glu:
10
0
0
10
10
0
10
0
0
10
20
10
30
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
30
0
10
0
10
% G
% His:
0
0
0
10
10
40
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
10
0
0
10
0
0
10
0
40
40
10
40
20
0
0
% K
% Leu:
10
10
10
10
0
10
0
10
10
10
0
0
0
10
0
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
40
10
0
0
10
30
0
0
20
0
10
40
% N
% Pro:
0
10
0
0
0
20
10
0
0
10
0
10
0
0
0
% P
% Gln:
30
0
10
0
0
10
40
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
0
0
0
0
10
0
30
40
10
0
0
0
0
20
0
% S
% Thr:
10
0
0
10
10
0
0
0
0
0
0
10
20
40
10
% T
% Val:
30
50
20
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _