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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPDYA All Species: 16.67
Human Site: S25 Identified Species: 40.74
UniProt: Q5MJ70 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5MJ70 NP_001008779.1 313 36463 S25 V K S G S N R S H Q P K K P I
Chimpanzee Pan troglodytes XP_515374 225 26070
Rhesus Macaque Macaca mulatta XP_001102674 313 36653 S25 V K S G S N R S H Q P K K P I
Dog Lupus familis XP_533235 197 22566
Cat Felis silvestris
Mouse Mus musculus Q5IBH7 310 36038 S25 V K S G S N R S H Q T R K P I
Rat Rattus norvegicus Q8R496 312 36205 S25 V K S G S N R S H Q T R K P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509302 311 36120 S24 V K S A A S R S H P P K K A V
Chicken Gallus gallus
Frog Xenopus laevis Q9PU13 299 34670 G25 V K Q V I G K G H P H A R V V
Zebra Danio Brachydanio rerio NP_001006091 289 33220 P26 S L Q I R R G P R K T R P G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782631 266 30955 R10 S V R G A G G R S G T S R E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.8 97.4 28.4 N.A. 83.3 85.9 N.A. 69.3 N.A. 39.6 49.8 N.A. N.A. N.A. N.A. 42.8
Protein Similarity: 100 71.8 98.7 38.6 N.A. 90 91 N.A. 80.8 N.A. 55.9 64.8 N.A. N.A. N.A. N.A. 59.4
P-Site Identity: 100 0 100 0 N.A. 86.6 80 N.A. 60 N.A. 20 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 0 100 0 N.A. 93.3 93.3 N.A. 80 N.A. 40 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 20 0 0 0 0 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 50 0 20 20 10 0 10 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 60 0 10 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 30 % I
% Lys: 0 60 0 0 0 0 10 0 0 10 0 30 50 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 20 30 0 10 40 0 % P
% Gln: 0 0 20 0 0 0 0 0 0 40 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 10 50 10 10 0 0 30 20 0 0 % R
% Ser: 20 0 50 0 40 10 0 50 10 0 0 10 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 40 0 0 0 10 % T
% Val: 60 10 0 10 0 0 0 0 0 0 0 0 0 10 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _